Bickerstaffe R, Mead J F
Department of Biophysics, Laboratory of Nuclear Medicine and Radiation Biology, UCLA School of Medicine, 90024, Los Angeles, California.
Lipids. 1968 Jul;3(4):317-20. doi: 10.1007/BF02530931.
Following intracerebral injection of(14)C-phosphatidylethanolamine and(3)H-chimyl alcohol into 18 day old rats, the ethanolamine phosphoglycerides were isolated and analyzed. The(14)C and(3)H activities in the dimethyl acetals derived from alkenyl acyl ethanolamine phosphoglycerides and in the glyceryl ethers derived from the alkyl acyl ethanolamine phosphoglycerides were measured. The absence of(14)C in the dimethyl acetals indicates that phosphatidyl ethanolamine is not transformed into phosphatidal ethanolamine under these circumstances. The increase with time of the(3)H content of the glyceryl ethers and dimethyl acetals indicates that chimyl alcohol was a precursor of both types of phospholipids.
在向18日龄大鼠脑内注射（14）C-磷脂酰乙醇胺和（3）H-鲨肝醇后，分离并分析了乙醇胺磷酸甘油酯。测定了衍生自烯基酰基乙醇胺磷酸甘油酯的二甲基缩醛和衍生自烷基酰基乙醇胺磷酸甘油酯的甘油醚中的（14）C和（3）H活性。二甲基缩醛中不存在（14）C表明在这些情况下磷脂酰乙醇胺不会转化为磷脂酰乙醇胺。甘油醚和二甲基缩醛中（3）H含量随时间的增加表明鲨肝醇是这两种磷脂的前体。
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