Suppr超能文献

[听神经瘤的假阳性诊断结果]

[False-positive diagnostic findings in acoustic neurinomas].

作者信息

Charabi S, Thomsen J C, Tos M

机构信息

Ore-, naese- og halsafdelingen, Københavns Amts Sygehus i Gentofte.

出版信息

Ugeskr Laeger. 1991 Dec 30;154(1):19-22.

PMID:1781059
Abstract

In the period from 1976 to 1990 Tos and Thomsen operated on 520 patients with acoustic neuromas using the translabyrinthine approach and five other patients were operated on via middle fossa approach. The diagnostic work up in all patients included: pure tone audiometry, tympanogram with acoustic reflexes, caloric test and brainstem audiometry. Since the late seventies, CT became the radiological investigation of choice to visualize the tumor. The first generation of CT failed to reveal tumors less than 1.5 cm in the extrameatal diameter, and pantopaque cisternography was necessary in some cases. The following generation of CT did not always reveal small intrameatal tumors, and false-negative results were reported. The incidence of false-positive CT findings in our series is calculated to be 0.6%. Three patients were operated on on account of false-positive CT. Peroperatively, adhesions in and around the internal porus were found in two cases while no pathology was found in the third case. Postoperatively, anacusis was observed in two cases. This could have been avoided if magnetic resonance imaging (MRI) with gadolinium contrast had been performed. In our opinion, MRI should be considered before a definitive surgical procedure is undertaken. Until MRI becomes more widely available, intravenous contrast-enhanced tomography followed by air cisternography is recommended in the diagnosis of small acoustic neuromas.

摘要

1976年至1990年期间,托斯和汤姆森采用经迷路入路为520例听神经瘤患者实施了手术,另有5例患者通过中颅窝入路进行了手术。所有患者的诊断检查包括:纯音听力测定、声反射鼓室图、冷热试验和脑干听力测定。自20世纪70年代末以来,CT成为可视化肿瘤的首选放射学检查方法。第一代CT无法显示外耳道直径小于1.5厘米的肿瘤,在某些情况下需要进行碘油脑池造影。下一代CT并不总是能显示出小的内耳道肿瘤,并且有假阴性结果的报道。我们系列中CT假阳性结果的发生率经计算为0.6%。有3例患者因CT假阳性而接受了手术。术中,2例在内耳道内及周围发现粘连,第3例未发现病变。术后,2例出现全聋。如果当时进行了钆增强磁共振成像(MRI),这种情况本可避免。我们认为,在进行确定性手术之前应考虑MRI。在MRI尚未更广泛应用之前,对于小听神经瘤的诊断,建议先进行静脉增强CT检查,然后进行气脑池造影。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验