Jaganathan Kirubanand, Ahmed Shwan, Henderson Alastair, Rané Abhay
James Paget Hospital, Great Yarmouth, UK.
Nat Clin Pract Urol. 2007 Sep;4(9):492-7. doi: 10.1038/ncpuro0856.
The association of testicular microlithiasis with testicular tumor and the management of incidentally detected testicular microlithiasis have generated a great deal of interest. We review the current literature on testicular microlithiasis with regard to its association with testicular tumor. This association seems complex. The available data suggest that men with incidental findings of testicular microlithiasis but who have otherwise normal testes are at low risk of developing testicular cancer. The only follow-up recommended is regular testicular self-examination. Testicular microlithiasis is, however, associated with a high risk of developing testicular malignancy in men with subfertility, history of contralateral testicular tumor or history of cryptorchidism. Regular testicular self-examination is recommended for follow-up of high-risk patients, but the role of surveillance with serial ultrasonography and measurement of tumor markers is still not clear.
睾丸微石症与睾丸肿瘤的关联以及偶然发现的睾丸微石症的处理引起了广泛关注。我们回顾了当前关于睾丸微石症与睾丸肿瘤关联的文献。这种关联似乎很复杂。现有数据表明,偶然发现睾丸微石症但睾丸其他方面正常的男性患睾丸癌的风险较低。唯一推荐的随访方式是定期进行睾丸自我检查。然而,对于不育、对侧睾丸肿瘤病史或隐睾病史的男性,睾丸微石症与发生睾丸恶性肿瘤的高风险相关。对于高危患者的随访,推荐定期进行睾丸自我检查,但连续超声检查和肿瘤标志物检测在监测中的作用仍不明确。