Gur A Y, Kesler A, Shopin L, Bornstein N M
Department of Neurology, The Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.
Acta Neurol Scand. 2007 Oct;116(4):239-42. doi: 10.1111/j.1600-0404.2007.00861.x.
The value of transcranial Doppler (TCD) ultrasonography in assessing patients with Idiopathic Intracranial Hypertension (IIH) is uncertain. We sought to determine the contribution of TCD to their evaluation.
Twenty-three patients with suspected IIH underwent TCD. Mean blood flow (BFV), peak systolic (PSV) and end-diastolic (EDV) velocities, and pulsatility (PI) and resistance (RI) indexes were obtained in the middle cerebral (MCA) and vertebral (VA) arteries and compared (Student's t-test) between patients with confirmed IIH and controls. IIH patients and controls were comparable in terms of age, gender and weight.
The mean +/- SD BFV(MCA), PSV(MCA), EDV(MCA) and PI(VA) in the 13 IIH patients were higher than in the ten controls (59 +/- 6.8, 94 +/- 28.5, 43 +/- 12.4, 0.86 +/- 0.16 and 50 +/- 8.6, 72 +/- 25.8, 32 +/- 11.5, 0.58 +/- 0.45 respectively, P < 0.05) but still within normal values. The mean +/- SD PI(MCA), RI(MCA) and RI(VA) values in the IIH patients and controls were similar.
TCD parameters had no useful unique features for monitoring IIH patients.
经颅多普勒（TCD）超声检查在评估特发性颅内高压（IIH）患者中的价值尚不确定。我们试图确定TCD在其评估中的作用。
23例疑似IIH患者接受了TCD检查。获取大脑中动脉（MCA）和椎动脉（VA）的平均血流（BFV）、收缩期峰值（PSV）和舒张末期（EDV）速度，以及搏动性（PI）和阻力（RI）指数，并在确诊的IIH患者和对照组之间进行比较（学生t检验）。IIH患者和对照组在年龄、性别和体重方面具有可比性。
13例IIH患者的平均±标准差BFV（MCA）、PSV（MCA）、EDV（MCA）和PI（VA）高于10例对照组（分别为59±6.8、94±28.5、43±12.4、0.86±0.16和50±8.6、72±25.8、32±11.5、0.58±0.45，P<0.05），但仍在正常范围内。IIH患者和对照组的平均±标准差PI（MCA）、RI（MCA）和RI（VA）值相似。
TCD参数对监测IIH患者没有有用的独特特征。
