Nitta Norihisa, Ohta Shinichi, Tanaka Toyohiko, Takazakura Ryutaro, Nagatani Yukihiro, Kono Naoaki, Sonoda Akinaga, Seko Ayumi, Furukawa Akira, Takahashi Masashi, Murata Kiyoshi, Tabata Yasuhiko
Department of Radiology, Shiga University of Medical Science, Tsukinowa-cho Otsu Shiga 520-2192, Japan.
Eur J Radiol. 2008 Sep;67(3):536-40. doi: 10.1016/j.ejrad.2007.07.021. Epub 2007 Sep 7.
The purpose of this study is to evaluate the embolization effects of gelatin microspheres (GMSs) when used as an embolic material for transcatheter arterial embolization (TAE) for several organs.
We prepared GMSs that dissolves in 5 days in extravasuclar tissue. GMSs were used in five cases in total, four cases with multiple liver tumors and one case with a pelvic bone tumor.
In all five cases, it was possible to treat the targeted tumors by TAE with GMSs. In the contrast-enhanced CT performed 2-4 weeks later, the embolized tumors did not show an enhancement effect. Passage of GMSs in the microcatheter was excellent.
GMSs showed sufficient potential to be used as an embolic material.
本研究的目的是评估明胶微球（GMSs）作为经导管动脉栓塞术（TAE）用于多个器官的栓塞材料时的栓塞效果。
我们制备了在血管外组织中5天内溶解的GMSs。GMSs总共用于5例患者，4例为多发性肝肿瘤，1例为骨盆骨肿瘤。
在所有5例患者中，使用GMSs通过TAE治疗靶向肿瘤是可行的。在2 - 4周后进行的对比增强CT检查中，栓塞的肿瘤未显示增强效果。GMSs在微导管中的通过情况良好。
GMSs显示出作为栓塞材料使用的充分潜力。
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