Rusby Jennifer E, Brachtel Elena F, Taghian Alphonse, Michaelson James S, Koerner Frederick C, Smith Barbara L
Division of Surgical Oncology, Yawkey 9A, Massachusetts General Hospital, Fruit St, Boston, MA 02114, USA.
Am J Surg. 2007 Oct;194(4):433-7. doi: 10.1016/j.amjsurg.2007.06.019.
Precise anatomical relationships between ducts and vasculature within the nipple remain unknown. This study investigated nipple microvessels and their position relative to ducts.
Nipple and duct bundle cross-sectional areas were measured in 48 specimens. Vessels located within the central duct bundle or within a peripheral rim were counted in 7 non-irradiated and 5 irradiated nipples.
Mean nipple diameter was 11.1 mm and duct bundle diameter 5.2 mm. A 2-mm and a 3-mm peripheral rim of nipple tissue would result in complete duct excision in 96% and 87% of sections, respectively. Twenty-nine percent of vessels are located in the duct bundle. A 2-mm rim contains 50%; a 3-mm rim contains 66%. Similar proportions were seen in irradiated nipples.
This study describes a strategy to balance duct removal with vascular preservation. Ducts can be excised leaving a rim of nipple tissue that contains a large proportion of microvessels.
乳头内导管与脉管系统之间精确的解剖关系尚不清楚。本研究调查了乳头微血管及其与导管的相对位置。
测量48个标本中乳头和导管束的横截面积。在7个未受照射和5个受照射的乳头中,对位于中央导管束或外周边缘内的血管进行计数。
乳头平均直径为11.1毫米,导管束直径为5.2毫米。乳头组织2毫米和3毫米的外周边缘分别会导致96%和87%的切片中导管完全切除。29%的血管位于导管束中。2毫米的边缘包含50%;3毫米的边缘包含66%。在受照射的乳头中也观察到类似比例。
本研究描述了一种平衡导管切除与血管保留的策略。可以切除导管,留下包含大部分微血管的乳头组织边缘。