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乔治·彼得斯奖。乳头内的微观解剖结构:对保乳手术的意义。

George Peters Award. Microscopic anatomy within the nipple: implications for nipple-sparing mastectomy.

作者信息

Rusby Jennifer E, Brachtel Elena F, Taghian Alphonse, Michaelson James S, Koerner Frederick C, Smith Barbara L

机构信息

Division of Surgical Oncology, Yawkey 9A, Massachusetts General Hospital, Fruit St, Boston, MA 02114, USA.

出版信息

Am J Surg. 2007 Oct;194(4):433-7. doi: 10.1016/j.amjsurg.2007.06.019.

Abstract

BACKGROUND

Precise anatomical relationships between ducts and vasculature within the nipple remain unknown. This study investigated nipple microvessels and their position relative to ducts.

METHODS

Nipple and duct bundle cross-sectional areas were measured in 48 specimens. Vessels located within the central duct bundle or within a peripheral rim were counted in 7 non-irradiated and 5 irradiated nipples.

RESULTS

Mean nipple diameter was 11.1 mm and duct bundle diameter 5.2 mm. A 2-mm and a 3-mm peripheral rim of nipple tissue would result in complete duct excision in 96% and 87% of sections, respectively. Twenty-nine percent of vessels are located in the duct bundle. A 2-mm rim contains 50%; a 3-mm rim contains 66%. Similar proportions were seen in irradiated nipples.

CONCLUSIONS

This study describes a strategy to balance duct removal with vascular preservation. Ducts can be excised leaving a rim of nipple tissue that contains a large proportion of microvessels.

摘要

背景

乳头内导管与脉管系统之间精确的解剖关系尚不清楚。本研究调查了乳头微血管及其与导管的相对位置。

方法

测量48个标本中乳头和导管束的横截面积。在7个未受照射和5个受照射的乳头中,对位于中央导管束或外周边缘内的血管进行计数。

结果

乳头平均直径为11.1毫米,导管束直径为5.2毫米。乳头组织2毫米和3毫米的外周边缘分别会导致96%和87%的切片中导管完全切除。29%的血管位于导管束中。2毫米的边缘包含50%;3毫米的边缘包含66%。在受照射的乳头中也观察到类似比例。

结论

本研究描述了一种平衡导管切除与血管保留的策略。可以切除导管,留下包含大部分微血管的乳头组织边缘。

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