Landi G, Anzalone N, Cella E, Boccardi E, Musicco M
Neurological Clinic, Ospedale Policlinico, Milan, Italy.
J Neurol Neurosurg Psychiatry. 1991 Dec;54(12):1063-8. doi: 10.1136/jnnp.54.12.1063.
To determine whether sensorimotor strokes should be considered as lacunar syndromes 34 consecutive patients with first-ever ischaemic sensorimotor stroke were evaluated and compared with 103 patients with non-lacunar infarcts and another 88 patients with lacunar infarcts. Potential thromboembolic sources were more frequent in patients with non-lacunar infarcts (p = 0.003, versus sensorimotor strokes). Although the overall prevalence of hypodense lesions at CT scan was not significantly different among the three groups, lacunar lesions were found in 47.1% of sensorimotor strokes, compared with 6.8% of non-lacunar infarcts (p less than 0.0001). In a mean follow up period of 28.7 months, the incidence of stroke and myocardial infarction among sensorimotor strokes was similar to that of patients with lacunar infarct, but significantly lower than in non-lacunar infarcts (p less than 0.05). These results demonstrate important differences between sensorimotor and non-lacunar infarcts, but quite similar findings in sensorimotor and lacunar strokes, and thus support the theory that sensorimotor strokes are commonly due to lacunar lesions.
为了确定感觉运动性卒中是否应被视为腔隙综合征，我们对34例首次发生缺血性感觉运动性卒中的患者进行了评估，并与103例非腔隙性梗死患者和另外88例腔隙性梗死患者进行了比较。非腔隙性梗死患者中潜在的血栓栓塞源更为常见（与感觉运动性卒中相比，p = 0.003）。尽管三组患者CT扫描低密度病变的总体患病率无显著差异，但感觉运动性卒中患者中47.1%发现有腔隙性病变，而非腔隙性梗死患者中这一比例为6.8%（p < 0.0001）。在平均28.7个月的随访期内，感觉运动性卒中患者的卒中和心肌梗死发生率与腔隙性梗死患者相似，但显著低于非腔隙性梗死患者（p < 0.05）。这些结果表明感觉运动性梗死与非腔隙性梗死之间存在重要差异，但感觉运动性卒中和腔隙性卒中的结果相当相似，因此支持感觉运动性卒中通常由腔隙性病变引起的理论。
