Patte Catherine, Dufour Christelle
Département de p'ediatrie, Institut Gustave-Roussy, 94805 Villejuif Cedex.
Rev Prat. 2007 May 31;57(10):1070-6.
Wilms' tumours, neuroblastomas occurring in patients aged less than 1 year or localized neuroblastomas in older patients, malignant germ cells tumours, Hodgkin's disease, and malignant non Hodgkin lymphomas can be cured in more than 80% of the cases with treatment strategies adapted to risks factors in each tumour. The knowledge of low risk groups of patients allows the decrease of cumulative doses of alkylating agents and anthracyclines and limits the use of irradiation in order to reduce long term sequelae.
肾母细胞瘤、1岁以下患者发生的神经母细胞瘤或老年患者的局限性神经母细胞瘤、恶性生殖细胞肿瘤、霍奇金病以及恶性非霍奇金淋巴瘤,采用针对各肿瘤危险因素的治疗策略,80%以上的病例可治愈。了解低风险患者群体有助于减少烷化剂和蒽环类药物的累积剂量,并限制放疗的使用,以减少长期后遗症。