Rathore M F A, Gill Z A, Malik A A, Farooq F
Spinal Rehabilitation Unit, Armed Forces Institute of Rehabilitation Medicine, Rawalpindi, Pakistan.
Spinal Cord. 2008 Apr;46(4):314-6. doi: 10.1038/sj.sc.3102120. Epub 2007 Sep 11.
A case report of spinal cord dysfunction following meningococcal meningitis.
To describe a rare complication of meningococcal meningitis.
Spinal Unit, Armed Forces Institute of Rehabilitation Medicine, Rawalpindi, Pakistan.
A young healthy male developed meningococcal meningitis followed by acute onset low thoracic flaccid paraplegia with complete motor and sensory loss and sphincter disturbance. He responded well to antibiotics but was not investigated for causes of paraplegia. While at home in a rural area, he developed pressure ulcers, anemia and depression. Magnetic resonance imaging of the whole spine and computed tomography scan of the brain performed after 4 and 10 weeks were normal.
The patient had a comprehensive rehabilitation at our institute. Recovery was complicated by ossification in the right thigh, which responded well to radiotherapy. At 1-year follow-up, the motor deficit and neurogenic bladder and bowel persisted and the patient remained wheelchair dependent for mobility.
Several mechanisms have been proposed to explain spinal cord damage after meningitis. These include spinal cord infarction; autoimmune-mediated inflammatory myelopathy and direct infection of the cord. Most probable cause of spinal cord dysfunction in this case was thoracic myelopathy.
一份关于脑膜炎球菌性脑膜炎后脊髓功能障碍的病例报告。
描述脑膜炎球菌性脑膜炎一种罕见的并发症。
巴基斯坦拉瓦尔品第武装部队康复医学研究所脊髓科。
一名年轻健康男性患上脑膜炎球菌性脑膜炎,随后急性发作胸段低位弛缓性截瘫,伴有完全性运动和感觉丧失以及括约肌功能障碍。他对抗生素反应良好,但未对截瘫原因进行调查。在农村家中时,他出现了压疮、贫血和抑郁。4周和10周后进行的全脊柱磁共振成像和脑部计算机断层扫描均正常。
该患者在我们研究所接受了全面康复治疗。康复过程因右大腿骨化而复杂化,骨化对放疗反应良好。在1年随访时,运动功能缺损以及神经源性膀胱和肠道功能障碍仍然存在,患者仍需依赖轮椅行动。
已提出多种机制来解释脑膜炎后脊髓损伤。这些机制包括脊髓梗死;自身免疫介导的炎性脊髓病以及脊髓的直接感染。该病例中脊髓功能障碍最可能的原因是胸段脊髓病。