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[运动皮层刺激治疗幻肢痛前的功能磁共振成像]

[Functional magnetic resonance imaging before motor cortex stimulation for phantom limb pain].

作者信息

Koppelstaetter F, Siedentopf C M, Rhomberg P, Lechner-Steinleitner S, Mottaghy F M, Eisner W, Golaszewski S M

机构信息

Univ.-Klinik für Radiologie II, Medizinische Universität, Innsbruck, Austria.

出版信息

Nervenarzt. 2007 Dec;78(12):1435-9. doi: 10.1007/s00115-007-2323-z.

Abstract

This study deals with the diagnostic value of functional magnetic resonance imaging (fMRI) in a patient with phantom limb pain following traumatic amputation of the right arm. After failure with medication, resection of stump neurinoma, and spinal cord stimulation, fMRI with evidence of cortical reorganization was performed. Tactile stimulation of the perioral region and motor imagery with cranial, tactile stimulation of the stump led to a caudal shift in fMRI activity. Subsequent motor cortex stimulation brought relief from the pain. By detecting cortical reorganization, fMRI contributes to the indication for motor cortex stimulation for phantom pain and aids in electrode positioning.

摘要

本研究探讨了功能磁共振成像(fMRI)对一名右臂外伤性截肢后出现幻肢痛患者的诊断价值。在药物治疗、残端神经瘤切除及脊髓刺激均无效后,进行了显示皮质重组的fMRI检查。对口周区域的触觉刺激以及对残端进行颅骨触觉刺激的运动想象导致了fMRI活动的尾侧移位。随后的运动皮层刺激缓解了疼痛。通过检测皮质重组,fMRI有助于确定幻肢痛运动皮层刺激的适应症,并辅助电极定位。

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