初次咬合综合征：29例咽旁间隙肿瘤患者的回顾性研究
First-bite syndrome: a review of 29 patients with parapharyngeal space tumor.
作者信息
Kawashima Yoshiyuki, Sumi Takuro, Sugimoto Taro, Kishimoto Seiji
机构信息
Department of Otolaryngology, Graduate School, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8519, Japan.
出版信息
Auris Nasus Larynx. 2008 Mar;35(1):109-13. doi: 10.1016/j.anl.2007.06.005. Epub 2007 Sep 11.
OBJECTIVE
The aim of this study is to clarify the etiology of first-bite syndrome.
METHODS
A total of 29 consecutive patients treated with a surgical resection for parapharyngeal space tumor between April 1999 and April 2005 were retrospectively reviewed.
RESULTS
Nine cases of first-bite syndrome were developed. Eight of those patients had undergone surgical ablation of the cervical sympathetic chain and/or external carotid artery. In two patients who underwent ablation of the sympathetic chain but in whom first-bite syndrome did not develop, the superior cervical ganglion was probably preserved.
CONCLUSION
The present findings strongly indicate that loss of sympathetic innervation to the parotid gland from the superior cervical ganglion causes first-bite syndrome. They also suggest that some residual or autonomous activity of the superior cervical ganglion could prevent development of first-bite syndrome even if the lower sympathetic trunk was ablated.
目的
本研究旨在阐明初咬综合征的病因。
方法
回顾性分析了1999年4月至2005年4月期间连续接受手术切除治疗的29例咽旁间隙肿瘤患者。
结果
发生了9例初咬综合征。其中8例患者接受了颈交感神经链和/或颈外动脉的手术切除。在2例接受交感神经链切除但未发生初咬综合征的患者中，颈上神经节可能得以保留。
结论
目前的研究结果有力地表明，颈上神经节对腮腺的交感神经支配丧失导致了初咬综合征。它们还表明，即使下交感干被切除，颈上神经节的一些残余或自主活动也可能防止初咬综合征的发生。
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