2,3-双（三甲基硅基）丁-1,3-二烯与酰氯之间发生的一种新型环化反应，可直接生成多取代呋喃。

A novel cyclization reaction between 2,3-bis(trimethylsilyl)buta-1,3-diene and acyl chlorides with straightforward formation of polysubstituted furans.

作者信息

Babudri Francesco, Cicco Stefania R, Farinola Gianluca M, Lopez Linda C, Naso Francesco, Pinto Vita

机构信息

Dipartimento di Chimica, Università degli Studi di Bari, via Orabona 4, I-70126 Bari, Italy.

出版信息

Chem Commun (Camb). 2007 Sep 28(36):3756-8. doi: 10.1039/b705257j. Epub 2007 Jul 9.

DOI:10.1039/b705257j

PMID:17851618

Abstract

A novel cyclization process of 2,3-bis(trimethylsilyl)buta-1,3-diene with various acyl chlorides in the presence of aluminium trichloride affords 2,5-disubstituted or 2,3,5-trisubstituted furans in short reaction time; a subsequent acylation process of the furan ring occurs if the reaction time is prolonged.

摘要

在三氯化铝存在下，2,3-双（三甲基硅基）丁-1,3-二烯与各种酰氯的新型环化过程能在短反应时间内得到2,5-二取代或2,3,5-三取代的呋喃；如果延长反应时间，呋喃环会发生后续的酰化过程。