Suzuki Shunji, Miyake Hidehiko
Department of Obstetrics and Gynecology, Japanese Red Cross Katsushika Maternity Hospital, 5-11-12 Tateishi, Katsushika-ku, Tokyo, Japan.
Arch Gynecol Obstet. 2008 Mar;277(3):225-7. doi: 10.1007/s00404-007-0461-y. Epub 2007 Sep 12.
To investigate obstetric outcomes in singleton pregnancies conceived by in vitro fertilization (IVF) to nulliparous women older than 35 compared to those of their younger counterparts.
Nulliparous women 35 years and older at delivery conceived by IVF (n = 89) were compared with nulliparous women 34 years and younger at delivery conceived by IVF (n = 48). Data included antenatal data, gestational age at delivery, maternal and neonatal complications and mode of delivery.
The incidence of pregnancy-induced hypertension in the younger group was significantly higher than that in the elderly group (13 vs. 3.4%, P = 0.043). There were no measurable differences in other obstetric outcomes such as placental abnormality, premature delivery or neonatal asphyxia between the two groups.
The current results suggest that obstetric complications in pregnancies conceived IVF are attributed to mechanisms other than those depend on advanced maternal age.
调查35岁以上未生育女性经体外受精（IVF）受孕的单胎妊娠的产科结局，并与年轻未生育女性的产科结局进行比较。
将分娩时年龄35岁及以上经IVF受孕的未生育女性（n = 89）与分娩时年龄34岁及以下经IVF受孕的未生育女性（n = 48）进行比较。数据包括产前数据、分娩时的孕周、母婴并发症及分娩方式。
年轻组妊娠高血压的发生率显著高于老年组（13% 对3.4%，P = 0.043）。两组在胎盘异常、早产或新生儿窒息等其他产科结局方面无显著差异。
目前的结果表明，IVF受孕妊娠的产科并发症归因于不依赖于高龄产妇的机制。
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