胸主动脉的有限元建模：包括主动脉根部运动以评估主动脉夹层风险。
Finite element modeling of the thoracic aorta: including aortic root motion to evaluate the risk of aortic dissection.
作者信息
Beller C J, Labrosse M R, Thubrikar M J, Robicsek F
机构信息
Department of Cardiac Surgery, University Hospital Heidelberg, INF 326, 69120, Heidelberg, Germany.
出版信息
J Med Eng Technol. 2008 Mar-Apr;32(2):167-70. doi: 10.1080/03091900600687672.
OBJECTIVE
We propose that the aortic root motion plays an important role in aortic dissection.
METHODS AND RESULTS
A finite element model of the aortic root, arch and branches of the arch was built to assess the influence of aortic root displacement and pressure on the aortic wall stress. The largest stress increase due to aortic root displacement was found at approximately 2 cm above the top of the aortic valve. There, the longitudinal stress increased by 50% to 0.32 MPa when 8.9 mm axial displacement was applied in addition to 120 mmHg luminal pressure. A similar result was observed when the pressure load was increased to 180 mmHg without axial displacement.
CONCLUSIONS
Both aortic root displacement and hypertension significantly increase the longitudinal stress in the ascending aorta, which could play a decisive role in the development of various aortic pathologies, including aortic dissection.
目的
我们提出主动脉根部运动在主动脉夹层中起重要作用。
方法与结果
建立主动脉根部、主动脉弓及其分支的有限元模型，以评估主动脉根部位移和压力对主动脉壁应力的影响。发现由于主动脉根部位移导致的最大应力增加出现在主动脉瓣顶部上方约2 cm处。在那里，当除了120 mmHg管腔内压力外再施加8.9 mm轴向位移时，纵向应力增加了50%，达到0.32 MPa。当压力负荷增加到180 mmHg而无轴向位移时，观察到类似结果。
结论
主动脉根部位移和高血压均显著增加升主动脉的纵向应力，这可能在包括主动脉夹层在内的各种主动脉病变的发展中起决定性作用。
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