息肉切除术后异时性结直肠腺瘤的右侧移位

Right-side shift of metachronous colorectal adenomas after polypectomy.

作者信息

Yamaji Yutaka, Mitsushima Toru, Yoshida Haruhiko, Watabe Hirotsugu, Okamoto Makoto, Ikuma Hitoshi, Wada Ryoichi, Kawabe Takao, Omata Masao

机构信息

Department of Gastroenterology, University of Tokyo, Bunkyo-ku, Tokyo, Japan.

出版信息

Scand J Gastroenterol. 2007 Dec;42(12):1466-72. doi: 10.1080/00365520701478543.

DOI:10.1080/00365520701478543

PMID:17852868

Abstract

OBJECTIVE

In our previous study, we showed that the development of adenomas in the right-side colon increased with aging in subjects with no colorectal neoplasms. The aim of the present study was to investigate the location of metachronous colorectal adenomas after endoscopic polypectomy.

MATERIAL AND METHODS

The records of a colonoscopic follow-up study on 2900 subjects after polypectomy were analyzed. The location was classified as the right-side colon and left-side colon at the splenic flexure. Subjects were classified into three groups according to distribution of adenomas at the initial two colonoscopies: those with adenomas located only in the left side (LL), adenomas in both the left side and right side (LR), and adenomas only in the right side (RR). Distribution of initial and metachronous adenomas was evaluated according to age.

RESULTS

The annual incidence rates of colorectal adenomas in the left-side colon were estimated to be 8.56%, 11.2%, and 5.71% in the LL, LR, and RR groups, respectively. The rates in the right side were 5.91%, 15.5%, and 9.38%, respectively. The incidence rates in the left side in the age groups <40, 40-49, 50-59, and > or =60 years were 6.93%, 8.08%, 8.33%, and 8.48%/year, respectively. Those in the right side were 4.91%, 7.27%, 9.86%, and 12.41%/year, respectively.

CONCLUSIONS

Although there may be individual predilection for right-side or left-side location of colorectal adenomas, aging tends to increase the number of adenomas in the right-side colon, while only modestly affecting those in the left-side colon.

摘要

目的

在我们之前的研究中，我们表明在无结直肠肿瘤的受试者中，右侧结肠腺瘤的发生随年龄增长而增加。本研究的目的是调查内镜下息肉切除术后异时性结直肠腺瘤的位置。

材料与方法

分析了2900名受试者息肉切除术后结肠镜随访研究的记录。位置分为脾曲处的右侧结肠和左侧结肠。根据最初两次结肠镜检查时腺瘤的分布，将受试者分为三组：腺瘤仅位于左侧的（LL）、左侧和右侧均有腺瘤的（LR）以及仅在右侧有腺瘤的（RR）。根据年龄评估初始腺瘤和异时性腺瘤的分布。

结果

LL、LR和RR组左侧结肠结直肠腺瘤的年发病率分别估计为8.56%、11.2%和5.71%。右侧的发病率分别为5.91%、15.5%和9.38%。年龄<40岁、40 - 49岁、50 - 59岁和≥60岁组左侧的发病率分别为每年6.93%、8.08%、8.33%和8.48%。右侧的发病率分别为每年4.91%、7.27%、9.86%和12.41%。