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择期结直肠手术中机械性肠道准备的应用

The use of mechanical bowel preparation in elective colorectal surgery.

作者信息

McCoubrey Alison S

机构信息

Department of Surgery, Antrim Area Hospital, Antrim BT41 2RL, United Kingdom.

出版信息

Ulster Med J. 2007 Sep;76(3):127-30.

Abstract

BACKGROUND

Mechanical bowel preparation (MBP) prior to elective colorectal surgery has been in use for many years. It is considered important in preventing post-operative infectious complications after colorectal surgery. The evidence to support these claims is lacking within the medical literature and yet this still remains standard practice in many hospitals. A literature search was undertaken to ascertain the evidence available regarding the use of MBP in elective colorectal surgery.

METHODS

The search included the databases PubMed, Medline and Embase using the keywords "mechanical bowel preparation", "bowel cleansing" and "elective colorectal surgery", a search of recent issues of relevant journals including Diseases of the Colon and Rectum and British Journal of Surgery and backward chaining from articles obtained.

RESULTS AND CONCLUSION

Most authors recommend that colorectal surgery is safe without pre-operative MBP but that there may some situations in which it may be beneficial (e.g. if there is a small tumour or the possible need for intra-operative colonoscopy). The implication for clinical practice in this situation is that there is not enough strength of evidence at present to recommend a change in practice. There is a need for further higher powered trials to try to answer this question definitively.

摘要

背景

择期结直肠手术前的机械性肠道准备(MBP)已应用多年。它被认为对预防结直肠手术后的感染性并发症很重要。医学文献中缺乏支持这些说法的证据,但在许多医院这仍然是标准做法。进行了文献检索以确定有关在择期结直肠手术中使用MBP的现有证据。

方法

检索包括使用关键词“机械性肠道准备”“肠道清洁”和“择期结直肠手术”的数据库PubMed、Medline和Embase,检索近期相关期刊(包括《结肠和直肠疾病》及《英国外科杂志》)的各期,并从获取的文章进行逆向追溯。

结果与结论

大多数作者建议,无术前MBP的结直肠手术是安全的,但在某些情况下可能有益(例如,如果有小肿瘤或可能需要术中结肠镜检查)。这种情况下对临床实践的影响是,目前没有足够有力的证据推荐改变实践做法。需要进一步开展更高质量的试验来明确回答这个问题。

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本文引用的文献

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