McDougald L R, Mathis G F, Seibert B P
Department of Poultry Science, University of Georgia, Athens 30602.
Avian Dis. 1991 Oct-Dec;35(4):863-8.
In a series of laboratory tests, diclazuril was evaluated for efficacy against Eimeria adenoeides, E. meleagrimitis, E. gallopavonis, and a mixture of the three species. Four isolates of each of the species were tested. When given at 0.5, 1.0, and 1.5 ppm in the feed, diclazuril was highly efficacious against all three species and against mixtures of the three, as judged by protection against mortality from coccidiosis, reduction in droppings scores, and improvement of weight gains compared with unmedicated controls. When diclazuril was given at 1.0 ppm, the improvement in droppings scores and weight gains was better than when 0.5 ppm of diclazuril was given. Increasing the dosage to 1.5 ppm did not appear to offer any consistent or significant improvement over 1.0 ppm.
在一系列实验室试验中，对地克珠利针对腺艾美耳球虫、火鸡艾美耳球虫、孔雀艾美耳球虫以及这三种球虫混合体的疗效进行了评估。对每种球虫的四个分离株进行了测试。通过与未用药对照组相比，依据预防球虫病死亡、降低粪便评分以及提高体重增加情况来判断，当在饲料中以0.5、1.0和1.5 ppm的剂量给予地克珠利时，其对所有三种球虫以及三种球虫的混合体均具有高效。当以1.0 ppm的剂量给予地克珠利时，粪便评分和体重增加情况的改善优于给予0.5 ppm地克珠利时。将剂量增加到1.5 ppm似乎并未比1.0 ppm带来任何持续或显著的改善。
