Abend Nicholas S, Bonnemann Carsten G, Licht Daniel J
Division of Neurology, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Pediatr Emerg Care. 2007 Sep;23(9):659-61. doi: 10.1097/PEC.0b013e31814b2ddd.
Malignant hypertension due to autonomic dysfunction is a known complication of Guillain-Barré syndrome. We describe a child who presented with status epilepticus secondary to hypertensive encephalopathy who, in recovery, was found to be areflexic. Nerve conduction studies confirmed the clinical diagnosis of Guillain-Barré syndrome. She was treated with antihypertensive and antiseizure medications and intravenous immune globulin with complete resolution of her autonomic symptoms and improvement in her weakness. Guillain-Barré syndrome may result in hypertensive encephalopathy that can manifest as status epilepticus before the onset of motor symptoms.
自主神经功能障碍所致的恶性高血压是吉兰-巴雷综合征已知的并发症。我们描述了一名儿童,其因高血压脑病继发癫痫持续状态,在恢复过程中被发现无反射。神经传导研究证实了吉兰-巴雷综合征的临床诊断。她接受了抗高血压和抗癫痫药物治疗以及静脉注射免疫球蛋白治疗,自主神经症状完全缓解,肌无力症状有所改善。吉兰-巴雷综合征可能导致高血压脑病,在运动症状出现之前可表现为癫痫持续状态。