海马硬化型颞叶癫痫患者磁共振成像颞极信号异常：液体衰减反转恢复序列研究
Temporal pole signal abnormality on MR imaging in temporal lobe epilepsy with hippocampal sclerosis: a fluid-attenuated inversion-recovery study.
作者信息
Carrete Henrique, Abdala Nitamar, Lin Kátia, Caboclo Luís Otávio, Centeno Ricardo Silva, Sakamoto Américo Ceiki, Szjenfeld Jacob, Nogueira Roberto Gomes, Yacubian Elza Márcia Targas
机构信息
Departamento de Diagnóstico por Imagem, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
出版信息
Arq Neuropsiquiatr. 2007 Sep;65(3A):553-60. doi: 10.1590/s0004-282x2007000400001.
OBJECTIVE
To determine the frequency and regional involvement of temporal pole signal abnormality (TPA) in patients with hippocampal sclerosis (HS) using fluid-attenuated inversion-recovery (FLAIR) MR imaging, and to correlate this feature with history.
METHOD
Coronal FLAIR images of the temporal pole were assessed in 120 patients with HS and in 30 normal subjects, to evaluate gray-white matter demarcation.
RESULTS
Ninety (75%) of 120 patients had associated TPA. The HS side made difference regarding the presence of TPA, with a left side prevalence (p=0.04, chi2 test). The anteromedial zone of temporal pole was affected in 27 (30%) out of 90 patients. In 63 (70%) patients the lateral zone were also affected. Patients with TPA were younger at seizure onset (p=0.018), but without association with duration of epilepsy.
CONCLUSION
Our FLAIR study show temporal pole signal abnormality in 3/4 of patients with HS, mainly seen on the anteromedial region, with a larger prevalence when the left hippocampus was involved.
目的
利用液体衰减反转恢复（FLAIR）磁共振成像确定海马硬化（HS）患者颞极信号异常（TPA）的频率和区域累及情况，并将此特征与病史相关联。
方法
对120例HS患者和30例正常受试者的颞极冠状位FLAIR图像进行评估，以评价灰白质分界。
结果
120例患者中有90例（75%）伴有TPA。HS的患病侧在TPA的存在方面存在差异，左侧患病率更高（p = 0.04，卡方检验）。90例患者中有27例（30%）的颞极前内侧区域受累。63例（70%）患者的外侧区域也受累。有TPA的患者癫痫发作起始时年龄更小（p = 0.018），但与癫痫病程无关。
结论
我们的FLAIR研究显示，3/4的HS患者存在颞极信号异常，主要见于前内侧区域，当左侧海马受累时患病率更高。
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