Huang Qiang, Dai Ding-Ke, Qian Xiao-Jun, Zhai Ren-You
Department of Radiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100021, China.
World J Gastroenterol. 2007 Oct 28;13(40):5376-9. doi: 10.3748/wjg.v13.i40.5376.
To investigate and evaluate the technical feasibility and clinical effectiveness of fluoroscopically guided peroral uncovered expandable metal stent placement to treat gastric outlet and duodenal obstructions.
Fifteen consecutive patients underwent peroral placement of Wallstent(TM) Enteral Endoprosthesis to treat gastric outlet and duodenal obstructions (14 malignant, 1 benign). All procedures were completed under fluoroscopic guidance without endoscopic assistance. Follow-up was completed until the patients died or were lost, and the clinical outcomes were analyzed.
The technique success rate was 100%, and the oral intake was maintained in 12 of 14 patients varying from 7 d to 270 d. Two patients remained unable to resume oral intake, although their stents were proven to be patent with the barium study. One patient with acute necrotizing pancreatitis underwent enteral stenting to treat intestinal obstruction, and nausea and vomiting disappeared. Ten patients died during the follow-up period, and their mean oral intake time was 50 d. No procedure-related complications occurred. Stent migration to the gastric antrum occurred in one patient 1 year after the procedure, a tumor grew at the proximal end of the stent in another patient 38 d post-stent insertion.
Fluoroscopically guided peroral metal stent implantation is a safe and effective method to treat malignant gastrointestinal obstructions, and complications can be ignored based on our short-term study. Indications for this procedure should be discreetly considered because a few patients may not benefit from gastrointestinal insertion, but some benign gastrointestinal obstructions can be treated using this procedure.
探讨和评估在X线透视引导下经口置入无覆膜可扩张金属支架治疗胃出口及十二指肠梗阻的技术可行性和临床疗效。
连续15例患者接受Wallstent™肠道内支架置入术治疗胃出口及十二指肠梗阻(14例恶性,1例良性)。所有操作均在X线透视引导下完成,无需内镜辅助。随访至患者死亡或失访,并分析临床结局。
技术成功率为100%,14例患者中有12例维持经口进食,时间从7天至270天不等。2例患者尽管经钡剂检查证实支架通畅,但仍无法恢复经口进食。1例急性坏死性胰腺炎患者接受肠道支架置入术治疗肠梗阻,恶心和呕吐消失。10例患者在随访期间死亡,其平均经口进食时间为50天。未发生与操作相关的并发症。1例患者术后1年支架移至胃窦,另1例患者支架置入后38天在支架近端出现肿瘤生长。
在X线透视引导下经口置入金属支架是治疗恶性胃肠道梗阻的一种安全有效的方法,基于我们的短期研究,并发症可忽略不计。该操作的适应证应谨慎考虑,因为少数患者可能无法从胃肠道置入中获益,但一些良性胃肠道梗阻可用此方法治疗。