Sharma Alok, Sen Achin K, Chaturvedi Nishith K, Yadav Rajbala
Department of Pathology, Dr. Ram Manohar Lohia Hospital, New Delhi.
Indian J Pathol Microbiol. 2007 Apr;50(2):326-8.
Myofibroblastoma of breast is an extremely rare, benign mesenchymal lesion composed ofmyofibroblasts. Less than seventy cases of this entity are reported in the literature. In spite of the widely varying morphological patterns, there are few characteristic cytological, histopathological, immunohistochemical, and ultrastructural features that permit its accurate identification among a vast group of mammary spindle cell tumours. We present the case ofa 60 year male presenting with a left breast nodule, interpreted as gynaecomastia on cytology. Histopathology however revealed characteristicfeatures of a myofibroblastoma, confirmed by immunohistochemistry.
乳腺肌纤维母细胞瘤是一种极其罕见的由肌纤维母细胞构成的良性间叶性病变。文献报道的该病例不足70例。尽管其形态学模式差异很大,但在众多乳腺梭形细胞瘤中,仍有一些特征性的细胞学、组织病理学、免疫组织化学和超微结构特征可用于准确识别。我们报告一例60岁男性患者,其左乳出现结节,细胞学检查诊断为男性乳房发育症。然而,组织病理学显示为肌纤维母细胞瘤的特征性表现,并经免疫组织化学证实。