Giulioni Marco, Zucchelli Mino, Riguzzi Patrizia, Marucci Gianluca, Tassinari Carlo Alberto, Calbucci Fabio
Division of Neurosurgery, Bellaria Hospital, Via Altura 3, 40139, Bologna, Italy.
J Clin Neurosci. 2007 Nov;14(11):1122-4. doi: 10.1016/j.jocn.2006.11.013. Epub 2007 Sep 19.
Cavernomas and cortical dysplasia are well-known causes of partial epilepsy. The association between cavernoma and cortical dysplasia in an epileptic patient has not yet been sufficiently documented. We report a case of long-term, drug-resistant, partial left temporal epilepsy associated with a cavernoma. According to the neurophysiological non-invasive presurgical study, the patient was submitted to a tailored left temporal resection. The histopathological study showed the coexistence of cavernoma and cortical dysplasia. This is an interesting combination of epilepsy-related pathologies that have so far not been documented.
海绵状血管瘤和皮质发育异常是部分性癫痫的常见病因。癫痫患者中海绵状血管瘤与皮质发育异常之间的关联尚未得到充分记录。我们报告一例与海绵状血管瘤相关的长期耐药性左侧颞叶部分性癫痫病例。根据神经生理学非侵入性术前研究,该患者接受了定制的左侧颞叶切除术。组织病理学研究显示海绵状血管瘤和皮质发育异常并存。这是一种迄今为止尚未见报道的有趣的癫痫相关病理组合。