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婴儿内侧颞叶肿块病变所致呼吸暂停:3例报告

Apnea caused by mesial temporal lobe mass lesions in infants: report of 3 cases.

作者信息

Miyagawa Tadashi, Sotero Marcio, Avellino Anthony M, Kuratani John, Saneto Russell P, Ellenbogen Richard G, Ojemann Jeffrey G

机构信息

Department of Neurological Surgery, University of Washington School of Medicine, Children's Hospital and Regional Medical Center, Seattle, Washington 98105, USA.

出版信息

J Child Neurol. 2007 Sep;22(9):1079-83. doi: 10.1177/0883073807306245.

Abstract

Apnea as an isolated manifestation of seizures is well described in neonates but is only occasionally observed in infants. This article reports 3 infants presenting with apneic events as the main manifestation of seizure, documented by video electroencephalogram, all with mesial temporal lobe lesions. The 3 infants, after normal pregnancy and delivery at term, showed the first apnea at the age of 4 to 10 months. Although the interictal electroencephalogram result was often normal, ictal video electroencephalogram in all infants showed focal rhythmic discharges with or without generalization. Magnetic resonance imaging showed an inferior mesial temporal lobe mass lesion in all infants. All patients underwent lesion removal, and they are seizure free with normal psychomotor development.

摘要

呼吸暂停作为癫痫发作的一种孤立表现,在新生儿中已有充分描述,但在婴儿中仅偶尔观察到。本文报告了3例以呼吸暂停事件为癫痫发作主要表现的婴儿,经视频脑电图证实,均有颞叶内侧病变。这3例婴儿在足月正常妊娠和分娩后,于4至10个月龄时首次出现呼吸暂停。尽管发作间期脑电图结果通常正常,但所有婴儿的发作期视频脑电图均显示有局灶性节律性放电,有或无泛化。磁共振成像显示所有婴儿均有颞叶内侧下部肿块病变。所有患者均接受了病变切除,目前无癫痫发作,精神运动发育正常。

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