Guldfred L-A, Lyhne D, Becker B C
Department of Otolaryngology, Roskilde County Hospital, Denmark.
J Laryngol Otol. 2008 Aug;122(8):818-23. doi: 10.1017/S0022215107000473. Epub 2007 Sep 25.
To describe the incidence trends, clinical presentation, management and outcome of acute epiglottitis in a Danish population after the introduction of Haemophilus influenzae type b vaccine.
Retrospective review of the health records of all patients discharged with a diagnosis of acute epiglottitis from the otolaryngology department, Roskilde County Hospital, Denmark, from 1996 to 2005.
One infant and 34 adults were identified. The incidence of acute epiglottitis in children was 0.02 cases/100,000/year. Before introduction of the H influenzae type b vaccination (1983-1992), the mean national incidence of acute epiglottitis was 4.9 cases/100,000/year. The incidence of acute epiglottitis in adults was constant, with a mean value of 1.9 cases/100,000/year. Twenty-nine per cent of the patients required an artificial airway, and respiratory distress was found to be associated with airway intervention (p = 0.010). All patients recovered completely.
In the H influenzae type b vaccine era, acute epiglottitis in children has almost disappeared. The incidence in the adult population has been constant. A discriminate approach to airway management seems safe in adults.
描述在引入b型流感嗜血杆菌疫苗后,丹麦人群中急性会厌炎的发病率趋势、临床表现、治疗及预后情况。
回顾性分析1996年至2005年丹麦罗斯基勒郡医院耳鼻喉科所有诊断为急性会厌炎并出院的患者的健康记录。
共识别出1名婴儿和34名成人。儿童急性会厌炎的发病率为0.02例/10万/年。在引入b型流感嗜血杆菌疫苗之前(1983 - 1992年),全国急性会厌炎的平均发病率为4.9例/10万/年。成人急性会厌炎的发病率保持稳定,平均值为1.9例/10万/年。29%的患者需要人工气道,且发现呼吸窘迫与气道干预相关(p = 0.010)。所有患者均完全康复。
在b型流感嗜血杆菌疫苗时代,儿童急性会厌炎几乎消失。成人中的发病率保持稳定。在成人中,一种有区别的气道管理方法似乎是安全的。