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一名前早产儿在接受第九次全身麻醉后出现术后高热、横纹肌溶解、临界温度及死亡情况。

Postoperative hyperthermia, rhabdomyolysis, critical temperature, and death in a former premature infant after his ninth general anesthetic.

作者信息

Phadke Aparna, Broadman Lynn M, Brandom Barbara W, Ozolek John, Davis Peter J

机构信息

Department of Anesthesiology, University of Pittsburgh School of Medicine and Children's Hospital of Pittsburgh, Pittsburgh, Pennsylvania, USA.

出版信息

Anesth Analg. 2007 Oct;105(4):977-80, table of contents. doi: 10.1213/01.ane.0000280935.90260.d0.

DOI:10.1213/01.ane.0000280935.90260.d0
PMID:17898376
Abstract

An 8-mo-old infant born at 24-wk of gestation died unexpectedly 12 h after his ninth uneventful general anesthetic. Preoperatively, he required low-flow nasal oxygen due to bronchopulmonary dysplasia, chronic diuretic therapy, and IV alimentation. As planned preoperatively, the infant remained tracheally intubated after his elective surgery and went to the Neonatal Intensive Care Unit in stable condition. However, over the next 6 h, he developed fever. The diagnosis of postoperative sepsis was considered. One hour before his death his temperature reached 43 degrees C. Autopsy documented Duchenne's muscular dystrophy and renal tubules containing myoglobin.

摘要

一名孕24周出生的8个月大婴儿,在第九次顺利的全身麻醉后12小时意外死亡。术前,由于支气管肺发育不良、长期利尿治疗和静脉营养,他需要低流量鼻导管吸氧。按照术前计划,婴儿在择期手术后仍保留气管插管,并以稳定状态转至新生儿重症监护病房。然而,在接下来的6小时内,他出现发热。考虑诊断为术后败血症。在他死亡前1小时,体温达到43摄氏度。尸检记录显示为杜氏肌营养不良症,肾小管内含有肌红蛋白。

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1
Postoperative hyperthermia, rhabdomyolysis, critical temperature, and death in a former premature infant after his ninth general anesthetic.一名前早产儿在接受第九次全身麻醉后出现术后高热、横纹肌溶解、临界温度及死亡情况。
Anesth Analg. 2007 Oct;105(4):977-80, table of contents. doi: 10.1213/01.ane.0000280935.90260.d0.
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Could this be malignant hyperthermia?这会是恶性高热吗?
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Rhabdomyolysis in association with Duchenne's muscular dystrophy.与杜氏肌营养不良相关的横纹肌溶解症。
Can J Anaesth. 1999 Jun;46(6):564-6. doi: 10.1007/BF03013547.
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