Pareja J, Moore J T
Hospital del INSALUD, Llerena, Badajoz.
Neurologia. 1991 Oct;6(8):276-80.
The diagnostic differential between narcolepsy and idiopathic hypersomnia may be difficult in those cases which clinically manifest only hypersomnia and the nocturnal polygraphic study does not show any differences between both diseases, particularly when the beginning of REM sleep is not presented in narcoleptic patients. The multiple sleep latency test is an objective test of daytime hypersomnia in both diseases. Moreover, if 2 or more REM periods are registered altogether in the 4 or 5 siestas studied, the test is highly suggestive of narcolepsy and permits sure differentiation with idiopathic hypersomnia. In the present study, the multiple sleep latency test permitted the diagnosis of the cases of oligosymptomatic narcolepsy and absence of the beginning of REM sleep.
对于那些仅临床表现为嗜睡且夜间多导睡眠监测未显示两种疾病有任何差异的病例,发作性睡病与特发性嗜睡症之间的鉴别诊断可能会很困难,尤其是当发作性睡病患者未出现快速眼动睡眠起始时。多次睡眠潜伏期试验是这两种疾病日间嗜睡的客观检测方法。此外,如果在研究的4或5次午睡中总共记录到2个或更多快速眼动期,则该试验强烈提示发作性睡病,并能与特发性嗜睡症明确区分。在本研究中,多次睡眠潜伏期试验有助于诊断症状较少的发作性睡病病例以及未出现快速眼动睡眠起始的情况。