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化脓性骶髂关节炎——儿童与成人患者的比较

Pyogenic sacroiliitis--a comparison between paediatric and adult patients.

作者信息

Wu M-S, Chang S-S, Lee S-H, Lee C-C

机构信息

Department of Emergency Medicine, Chang Gung Memorial Hospital, Chang Gung University, College of Medicine, Taipei, Taiwan.

出版信息

Rheumatology (Oxford). 2007 Nov;46(11):1684-7. doi: 10.1093/rheumatology/kem201. Epub 2007 Sep 26.

Abstract

BACKGROUND

Pyogenic sacroiliitis is a rare cause of hip pain and fever. We aim to report a series of 33 patients with pyogenic sacroiliitis and to investigate the differences among paediatric and adult cases.

METHODS

Clinical and laboratory data of 33 cases who were admitted to the emergency department with a confirmed discharge diagnosis of pyogenic sacroiliitis between 1996 and 2005 were assessed. All patients were divided into paediatric and adult groups by the age of 15 yr. The features of pyogenic sacroiliitis and clinical outcome were compared among the two groups. Several factors were analysed including gender, age, clinical signs and symptoms, laboratory tests, radiological examinations and scintigraphy.

RESULTS

Among the all included patients, females were attacked more frequently than males (3: 1). One-third of patients had concurrent infections, of which urinary tract infections were the most common (41.6%). Compared with adult patients, paediatric patients tend to have fewer comorbid immunocompromized conditions, fewer concurrent infections, more equality in gender distribution and more presentations of weight bearing difficulty. Staphylococcus aureus was the main blood culture isolate from paediatric patients (80%), but only accounted for half of those from adult patients. Group B streptococcus and Salmonella spp. were not uncommon in the adult patients. Scintigraphic bone scan has the highest sensitivity (93.3%) and remains the image modality of choice. When local abscess formation is suspected, computed tomography or magnetic resonance imaging may be the preferred method used for examination.

CONCLUSION

This case series should alert the physicians to the possibility of pyogenic sacroiliitis and the difference between paediatric and adult patients.

摘要

背景

化脓性骶髂关节炎是导致髋关节疼痛和发热的罕见病因。我们旨在报告一组33例化脓性骶髂关节炎患者,并研究儿童和成人病例之间的差异。

方法

评估了1996年至2005年间因确诊为化脓性骶髂关节炎而入住急诊科的33例患者的临床和实验室数据。所有患者按15岁的年龄界限分为儿童组和成人组。比较了两组化脓性骶髂关节炎的特征和临床结局。分析了几个因素,包括性别、年龄、临床体征和症状、实验室检查、影像学检查和骨闪烁显像。

结果

在所有纳入的患者中,女性发病比男性更频繁(3:1)。三分之一的患者有合并感染,其中尿路感染最为常见(41.6%)。与成年患者相比,儿童患者往往合并免疫功能低下的情况较少,合并感染较少,性别分布更均衡,负重困难的表现更多。金黄色葡萄球菌是儿童患者血培养的主要分离菌株(80%),但在成年患者中仅占一半。B组链球菌和沙门氏菌在成年患者中并不少见。骨闪烁显像的敏感性最高(93.3%),仍然是首选的成像方式。当怀疑有局部脓肿形成时,计算机断层扫描或磁共振成像可能是首选的检查方法。

结论

该病例系列应提醒医生注意化脓性骶髂关节炎的可能性以及儿童和成人患者之间的差异。

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