Pietrzak Robert H, Wagner Julie A, Petry Nancy M
Department of Psychiatry, University of Connecticut Health Center, Farmington, CT 06030-3944, USA.
J Gerontol B Psychol Sci Soc Sci. 2007 Sep;62(5):P295-9. doi: 10.1093/geronb/62.5.p295.
We evaluated the relationship between seven personality disorders listed in the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders and coronary heart disease (CHD) in a nationally representative sample of U.S. older adults. We analyzed data on 10,573 adults aged 60 or older from the National Epidemiologic Survey on Alcohol and Related Conditions. In our results, we found that 13.30% of older adults reported a diagnosis of CHD confirmed by a health professional. Age (odds ratio or OR = 1.04), morbid obesity (OR = 1.59), hypertension (OR = 2.30), nicotine dependence (OR = 1.39), any drug use disorder (OR = 2.13), and any mood disorder (OR = 1.87) increased the odds of having CHD. Female gender (OR = 0.72) and social drinking (OR = 0.71) decreased the odds of having CHD. Controlling for these variables, we found that avoidant (OR = 1.80), schizoid (OR = 1.63), and obsessive-compulsive (OR = 1.37) personality disorders increased the odds of having CHD. Personality disorders may increase the risk of CHD in older adults. Putative mechanisms and directions for future research are proposed.
我们在美国老年人具有全国代表性的样本中,评估了《精神疾病诊断与统计手册》第四版中列出的七种人格障碍与冠心病(CHD)之间的关系。我们分析了来自全国酒精及相关疾病流行病学调查的10573名60岁及以上成年人的数据。在我们的研究结果中,我们发现13.30%的老年人报告称经健康专业人员确诊患有冠心病。年龄(比值比或OR = 1.04)、病态肥胖(OR = 1.59)、高血压(OR = 2.30)、尼古丁依赖(OR = 1.39)、任何药物使用障碍(OR = 2.13)以及任何情绪障碍(OR = 1.87)都会增加患冠心病的几率。女性(OR = 0.72)和社交性饮酒(OR = 0.71)会降低患冠心病的几率。在控制了这些变量后,我们发现回避型(OR = 1.80)、分裂样(OR = 1.63)和强迫型(OR = 1.37)人格障碍会增加患冠心病的几率。人格障碍可能会增加老年人患冠心病的风险。本文提出了可能的机制以及未来研究的方向。