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肥胖对全髋关节或膝关节置换术风险的作用。

Role of obesity on the risk for total hip or knee arthroplasty.

作者信息

Bourne Robert, Mukhi Shaheena, Zhu Naisu, Keresteci Margaret, Marin Mihaela

机构信息

University of Western Ontario, London, ON, Canada.

出版信息

Clin Orthop Relat Res. 2007 Dec;465:185-8. doi: 10.1097/BLO.0b013e3181576035.

Abstract

We asked whether there was an association between obesity levels and subsequent THA or TKA using data from 54,406 THA and TKA patients entered into the Canadian Joint Replacement Registry. We compared these patients with a sample of the Canadian population using the Canadian Community Health Survey of 2006. We analyzed information from the Canadian Joint Replacement Registry to quantify the relative risk for THA or TKA in Canada for specific body mass index categories. In reference to the acceptable weight category of body mass index less than 25 kg/m2, the risk for TKA and THA was 3.20- and 1.92-fold higher, respectively, for overweight individuals (body mass index 25-29.9 kg/m2); 8.53- (TKA) and 3.42-fold (THA) higher for those in the obese Class I (body mass index 30-34.9 kg/m2) category; 18.73- (TKA) and 5.24-fold (THA) higher for those identified in obese Class II (body mass index 35-39.9 kg/m2); and 32.73- (TKA) and 8.56-fold (THA) higher for people in obese Class III group (body mass index > 40 kg/m2). Thus, our data support an association between obesity and subsequent THA and TKA.

摘要

我们利用加拿大关节置换登记处收录的54406例全髋关节置换术(THA)和全膝关节置换术(TKA)患者的数据,探究肥胖水平与后续THA或TKA之间是否存在关联。我们将这些患者与2006年加拿大社区健康调查中的加拿大人群样本进行比较。我们分析了加拿大关节置换登记处的信息,以量化加拿大特定体重指数类别下THA或TKA的相对风险。与体重指数小于25kg/m²的可接受体重类别相比,超重个体(体重指数25 - 29.9kg/m²)进行TKA和THA的风险分别高3.20倍和1.92倍;I类肥胖个体(体重指数30 - 34.9kg/m²)进行TKA和THA的风险分别高8.53倍和3.42倍;II类肥胖个体(体重指数35 - 39.9kg/m²)进行TKA和THA的风险分别高18.73倍和5.24倍;III类肥胖组个体(体重指数>40kg/m²)进行TKA和THA的风险分别高32.73倍和8.56倍。因此,我们的数据支持肥胖与后续THA和TKA之间存在关联。

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