Izci Y, Secer H I, Gönül E, Ongürü O
Department of Neurosurgery, Gulhane Military Medical Academy, Ankara, Turkey.
Clin Neuropathol. 2007 Sep-Oct;26(5):219-23. doi: 10.5414/npp26219.
Simultaneously occurring multiple primary brain tumors of different histological types are rare, and the coexistence of schwannoma and meningioma in the same cerebellopontine angle (CPA) without neurofibromatosis is extremely rare. A 57-year-old female patient presented with headache, speech disturbance, left facial numbness and deafness in the left ear. Magnetic resonance imaging demonstrated two different tumors in the left CPA. These tumors were not in continuity. The tumors were totally removed through the left suboccipital approach. Histopathological examination revealed that the large tumor was a vestibular schwannoma and the smaller was a meningioma. Neurofibromatosis was not diagnosed in the patient. No recurrence was observed at the end of 9 years after the operation. The simultaneous occurrence of vestibular schwannoma and meningioma in the CPA appears coincidental. This association must be kept in mind if two different tumors are detected radiologically in the same CPA.
同时出现不同组织学类型的多发性原发性脑肿瘤很罕见，在没有神经纤维瘤病的情况下，同一小脑脑桥角（CPA）内同时存在神经鞘瘤和脑膜瘤极为罕见。一名57岁女性患者出现头痛、言语障碍、左侧面部麻木和左耳听力丧失。磁共振成像显示左侧CPA有两个不同的肿瘤。这些肿瘤不连续。通过左侧枕下入路将肿瘤完全切除。组织病理学检查显示，较大的肿瘤是前庭神经鞘瘤，较小的是脑膜瘤。该患者未诊断出神经纤维瘤病。术后9年末未观察到复发。CPA内前庭神经鞘瘤和脑膜瘤同时出现似乎是巧合。如果在同一CPA中通过影像学检测到两个不同的肿瘤，必须牢记这种关联。
