Gomel Victor
Department of Obstetrics and Gynecology, Faculty of Medicine, University of British Columbia, Vancouver, BC, Canada.
Reprod Biomed Online. 2007 Oct;15(4):403-7. doi: 10.1016/s1472-6483(10)60365-3.
Two treatment options are available to women who wish to become pregnant after having had tubal sterilization: microsurgical reversal or IVF. The first approach is designed to restore tubal function, whereas the second replaces it. The first, to be successful, requires the presence of sufficient tubal length and normal or treatable fertility parameters. Treatment should therefore be individualized, based upon the findings of the couple's investigation, their wishes and the costs involved. The age of the female is the most important factor that affects the outcome with both treatment options. The live birth rate per cycle with IVF is 28%, but only 65.8% are singletons; 31.0% are twins and 3.2% triplets or more. Microsurgical tubal anastomosis yields a birth rate that exceeds 55%, without increased risk of multiple pregnancy. It offers the couple multiple cycles in which to achieve conception naturally, and the opportunity to have more than one pregnancy from a single intervention. The real dilemma lies with the 'industrialization' of IVF, and its frequent use as primary treatment for infertility. The dilemma is heightened by the fact that reconstructive tubal microsurgery is being taught and practised less and less, thereby eliminating this credible surgical option in most centres.
对于输卵管绝育术后希望怀孕的女性,有两种治疗选择:显微外科输卵管复通术或体外受精(IVF)。第一种方法旨在恢复输卵管功能,而第二种方法则是替代输卵管功能。第一种方法若要成功,需要有足够的输卵管长度以及正常或可治疗的生育参数。因此,应根据夫妻双方检查结果、他们的意愿以及相关费用进行个体化治疗。女性年龄是影响这两种治疗选择结果的最重要因素。IVF每个周期的活产率为28%,但单胎仅占65.8%;31.0%为双胞胎,3.2%为三胞胎或更多。显微外科输卵管吻合术的出生率超过55%,且多胎妊娠风险不会增加。它为夫妻提供了多个自然受孕周期,以及单次干预后多次怀孕的机会。真正的困境在于IVF的“产业化”,以及它经常被用作不孕症的主要治疗方法。由于讲授和实施输卵管显微重建手术的情况越来越少,从而在大多数中心消除了这种可靠的手术选择,这一困境更加突出。