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T3/T4胸交感神经切除术及代偿性出汗治疗手掌多汗症

T3/T4 thoracic sympathictomy and compensatory sweating in treatment of palmar hyperhidrosis.

作者信息

Yang Jie, Tan Jia-Ju, Ye Guo-Lin, Gu Wei-Quan, Wang Jun, Liu Yan-Guo

机构信息

Department of Thoracic Surgery, First People's Hospital of Fushan, Fushan, China.

出版信息

Chin Med J (Engl). 2007 Sep 20;120(18):1574-7.

Abstract

BACKGROUND

Compensatory sweating (CS) is one of the most common postoperative complications after thoracic sympathectomy, sympathicotomy or endoscopic sympathetic block (ESB) for palmar hyperhidrosis. This study was conducted to examine the relevance between CS and the sympathetic segment being transected in the surgical treatment of palmar hyperhidrosis, and thus to detect the potential mechanism of the occurrence of CS.

METHODS

Between October 2004 and June 2006, 163 patients with primary hyperhidrosis were randomly divided into two groups, T(3) sympathicotomy (78 patients) and T(4) sympathicotomy (85), who were operated upon under general anesthesia via single lumen intubation and intercostal video-mediastinoscopy (VM).

RESULTS

No morbidity or mortality occurred. Palmar hyperhidrosis was cured in all patients. Follow-up (mean (13.8 +/- 6.2) months) showed no recurrence of palmar hyperhidrosis. The difference of rates of mild CS in groups T(3) and T(4) was of no statistical significance. The rate of moderate CS was significantly lower in group T(4) than in group T(3). No severe CS occurred.

CONCLUSION

The rates of occurrence and severity of CS are lowered with the lower sympathetic chain being transected.

摘要

背景

代偿性多汗(CS)是胸腔交感神经切除术、交感神经切断术或内镜下交感神经阻滞(ESB)治疗手掌多汗症后最常见的术后并发症之一。本研究旨在探讨手掌多汗症手术治疗中CS与交感神经节段切断之间的相关性,从而探寻CS发生的潜在机制。

方法

2004年10月至2006年6月,163例原发性多汗症患者随机分为两组,T(3)交感神经切断术组(78例)和T(4)交感神经切断术组(85例),均在全身麻醉下单腔气管插管及经肋间电视纵隔镜(VM)下进行手术。

结果

无 morbidity 或 mortality 发生。所有患者手掌多汗症均治愈。随访(平均(13.8±6.2)个月)显示手掌多汗症无复发。T(3)组和T(4)组轻度CS发生率差异无统计学意义。T(4)组中度CS发生率显著低于T(3)组。无重度CS发生。

结论

切断较低的交感神经链可降低CS的发生率和严重程度。

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