Suppr超能文献

膝关节单髁骨关节同种异体移植

Unicondylar osteoarticular allografts of the knee.

作者信息

Muscolo D Luis, Ayerza Miguel A, Aponte-Tinao Luis A, Abalo Eduardo, Farfalli German

机构信息

Institute of Orthopedics Carlos E. Ottolenghi, Italian Hospital of Buenos Aires, Potosí 4215, (1199) Buenos Aires, Argentina.

出版信息

J Bone Joint Surg Am. 2007 Oct;89(10):2137-42. doi: 10.2106/JBJS.F.01277.

Abstract

BACKGROUND

In the management of a resected distal femoral or proximal tibial condyle as the result of tumor or trauma, a unicondylar osteoarticular allograft is currently the only reconstructive option that avoids the sacrifice of the unaffected condyle. The purposes of this study were to perform a survival analysis of unicondylar osteoarticular allografts of the knee and to evaluate the complications.

METHODS

We retrospectively reviewed the results of forty large unicondylar osteoarticular allograft procedures in thirty-eight patients who were followed for a mean of eleven years. Twenty-nine allografts were femoral transplants and included eleven medial and eighteen lateral femoral condyles. Eleven allografts were tibial transplants, including four medial and seven lateral tibial condyles. The procedure was performed after a tumor resection in thirty-six patients and to replace condylar loss after a severe open fracture in the remaining two patients. Complications were analyzed, and allograft survival from the date of implantation to the date of revision or the time of the latest follow-up was determined. Functional and radiographic results were documented according to the Musculoskeletal Tumor Society scoring system at the time of the latest follow-up.

RESULTS

One patient died of tumor-related causes without allograft failure before the two-year follow-up evaluation. The global rate of allograft survival at both five and ten years was 85%, with a mean follow-up of 148 months. In six patients, the allografts were removed at an average of twenty-six months (range, six to forty-eight months) and these were considered failures. All six patients underwent a second allograft procedure including two new unicondylar and four bicondylar reconstructions. The mean radiographic score for the thirty-three surviving allografts evaluated was 89%, with an average functional score of 27 of a possible 30 points.

CONCLUSIONS

Unicondylar osteoarticular allografts of the knee appear to be a reliable alternative for patients in whom reconstruction of massive osteoarticular bone loss is limited to one condyle of the femur or the tibia.

摘要

背景

在因肿瘤或创伤而进行的股骨远端或胫骨近端髁切除的治疗中,单髁骨关节异体移植目前是唯一一种避免牺牲未受影响髁的重建选择。本研究的目的是对膝关节单髁骨关节异体移植进行生存分析并评估并发症。

方法

我们回顾性分析了38例患者接受的40例大型单髁骨关节异体移植手术的结果,这些患者的平均随访时间为11年。29例异体移植为股骨移植,包括11例内侧股骨髁和18例外侧股骨髁。11例异体移植为胫骨移植,包括4例内侧胫骨髁和7例外侧胫骨髁。36例患者在肿瘤切除后进行了该手术,其余2例患者在严重开放性骨折后进行该手术以替代髁的缺失。分析并发症,并确定异体移植从植入日期到翻修日期或最新随访时间的生存率。根据肌肉骨骼肿瘤学会评分系统记录最新随访时的功能和影像学结果。

结果

1例患者在两年随访评估前因肿瘤相关原因死亡,异体移植未失败。5年和10年时异体移植的总体生存率均为85%,平均随访时间为148个月。6例患者的异体移植平均在26个月(范围6至48个月)时被取出,这些被视为失败。所有6例患者均接受了第二次异体移植手术,包括2例新的单髁和4例双髁重建。评估的33例存活异体移植的平均影像学评分为89%,平均功能评分为27分(满分30分)。

结论

对于股骨或胫骨单髁出现大块骨关节骨丢失需要重建的患者,膝关节单髁骨关节异体移植似乎是一种可靠的选择。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验