相似文献
1
Obesity and the beta cell: lessons from leptin.
J Clin Invest. 2007 Oct;117(10):2753-6. doi: 10.1172/JCI33528.
2
Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice.
J Clin Invest. 2007 Oct;117(10):2860-8. doi: 10.1172/JCI30910.
3
Hyperinsulinemia precedes insulin resistance in mice lacking pancreatic beta-cell leptin signaling.
Endocrinology. 2010 Sep;151(9):4178-86. doi: 10.1210/en.2010-0102. Epub 2010 Jul 14.
4
Leptin signaling regulates glucose homeostasis, but not adipostasis, in the zebrafish.
Proc Natl Acad Sci U S A. 2016 Mar 15;113(11):3084-9. doi: 10.1073/pnas.1513212113. Epub 2016 Feb 22.
5
Restoration of in β cells of null mice does not prevent hyperinsulinemia and hyperglycemia.
Mol Metab. 2017 Apr 11;6(6):585-593. doi: 10.1016/j.molmet.2017.04.003. eCollection 2017 Jun.
6
Impaired Ca(2+) signaling in β-cells lacking leptin receptors by Cre-loxP recombination.
PLoS One. 2013 Aug 1;8(8):e71075. doi: 10.1371/journal.pone.0071075. Print 2013.
7
The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis.
Cell Metab. 2006 Oct;4(4):291-302. doi: 10.1016/j.cmet.2006.09.005.
8
LIM-homeodomain transcription factor Isl-1 mediates the effect of leptin on insulin secretion in mice.
J Biol Chem. 2013 Apr 26;288(17):12395-405. doi: 10.1074/jbc.M113.450536. Epub 2013 Mar 15.
9
Disruption of hypothalamic leptin signaling in mice leads to early-onset obesity, but physiological adaptations in mature animals stabilize adiposity levels.
J Clin Invest. 2010 Aug;120(8):2931-41. doi: 10.1172/JCI41985. Epub 2010 Jul 1.
10
Neuroanatomy of body weight control: lessons learned from leptin.
J Clin Invest. 2011 Jun;121(6):2152-5. doi: 10.1172/JCI58027. Epub 2011 May 23.
引用本文的文献
1
Sex-specific associations between body composition and depression among U.S. adults: a cross-sectional study.
Lipids Health Dis. 2025 Jan 18;24(1):15. doi: 10.1186/s12944-025-02437-5.
2
Pathophysiology of obesity and its associated diseases.
Acta Pharm Sin B. 2023 Jun;13(6):2403-2424. doi: 10.1016/j.apsb.2023.01.012. Epub 2023 Jan 13.
3
High dietary fat and sucrose results in an extensive and time-dependent deterioration in health of multiple physiological systems in mice.
J Biol Chem. 2018 Apr 13;293(15):5731-5745. doi: 10.1074/jbc.RA117.000808. Epub 2018 Feb 13.
4
Metabolic and bone effects of high-fat diet in adult zebrafish.
Endocrine. 2018 Aug;61(2):317-326. doi: 10.1007/s12020-017-1494-z. Epub 2017 Dec 22.
5
High-fat diet induces systemic B-cell repertoire changes associated with insulin resistance.
Mucosal Immunol. 2017 Nov;10(6):1468-1479. doi: 10.1038/mi.2017.25. Epub 2017 Apr 19.
6
Prolactin regulatory element-binding protein is involved in suppression of the adiponectin gene in vivo.
J Endocrinol Invest. 2017 Apr;40(4):437-445. doi: 10.1007/s40618-016-0589-3. Epub 2016 Dec 2.
7
Disease activity, obesity, functional disability, and depression in patients with rheumatoid arthritis : Impact on lipid status, glycoregulation, and risk for coronary heart disease.
Z Rheumatol. 2016 Sep;75(7):716-22. doi: 10.1007/s00393-015-1661-7.
8
Limited impact on glucose homeostasis of leptin receptor deletion from insulin- or proglucagon-expressing cells.
Mol Metab. 2015 Jun 25;4(9):619-30. doi: 10.1016/j.molmet.2015.06.007. eCollection 2015 Sep.
9
Dietary intakes and leptin concentrations.
ARYA Atheroscler. 2014 Sep;10(5):266-72.
10
The control of insulin secretion by adipokines: current evidence for adipocyte-beta cell endocrine signalling in metabolic homeostasis.
Mamm Genome. 2014 Oct;25(9-10):442-54. doi: 10.1007/s00335-014-9538-7. Epub 2014 Aug 22.
本文引用的文献
1
Disruption of leptin receptor expression in the pancreas directly affects beta cell growth and function in mice.
J Clin Invest. 2007 Oct;117(10):2860-8. doi: 10.1172/JCI30910.
2
The pancreatic beta cell is a key site for mediating the effects of leptin on glucose homeostasis.
Cell Metab. 2006 Oct;4(4):291-302. doi: 10.1016/j.cmet.2006.09.005.
3
C16:0 sulfatide inhibits insulin secretion in rat beta-cells by reducing the sensitivity of KATP channels to ATP inhibition.
Diabetes. 2006 Oct;55(10):2826-34. doi: 10.2337/db05-1355.
4
A novel leptin signalling pathway via PTEN inhibition in hypothalamic cell lines and pancreatic beta-cells.
EMBO J. 2006 Jun 7;25(11):2377-87. doi: 10.1038/sj.emboj.7601118. Epub 2006 May 4.
5
Metabolic regulation of the pancreatic beta-cell ATP-sensitive K+ channel: a pas de deux.
Diabetes. 2004 Dec;53 Suppl 3:S113-22. doi: 10.2337/diabetes.53.suppl_3.s113.
6
An allelic series for the leptin receptor gene generated by CRE and FLP recombinase.
Mamm Genome. 2004 Sep;15(9):677-85. doi: 10.1007/s00335-004-2340-1.
7
Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia.
Diabetes. 2003 Feb;52(2):227-31. doi: 10.2337/diabetes.52.2.227.
8
Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in beta-cell adaptation and failure in the etiology of diabetes.
Diabetes. 2002 Dec;51 Suppl 3:S405-13. doi: 10.2337/diabetes.51.2007.s405.
9
The physiology of cellular liporegulation.
Annu Rev Physiol. 2003;65:333-47. doi: 10.1146/annurev.physiol.65.092101.142622. Epub 2002 May 1.
10
Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency.
J Clin Invest. 2002 Oct;110(8):1093-103. doi: 10.1172/JCI15693.
Zotero 插件