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随机临床试验:对有症状和无症状颅外颈动脉闭塞性疾病临床实践的影响。

Randomized clinical trials: impact on clinical practice for symptomatic and asymptomatic extracranial carotid occlusive disease.

作者信息

Hobson Robert W

机构信息

University of Medicine and Dentistry of New Jersey, New Jersey Medical School, Newark, New Jersey, USA.

出版信息

Perspect Vasc Surg Endovasc Ther. 2007 Sep;19(3):215-9. doi: 10.1177/1531003507305267.

Abstract

Carotid artery stenting (CAS) has emerged as a useful and potentially less invasive alternative to carotid endarterectomy (CEA) for the treatment of extracranial carotid stenoses. In this regard, it has been suggested that specific patient subgroups who may benefit from CAS including those with significant medical comorbidities, recurrent stenosis, anatomically inaccessible lesions, and a hostile neck. However, the purpose of this report is to evaluate whether or not CAS should replace CEA in the treatment of symptomatic and asymptomatic disease in better risk patients, also. This report contains results from recently published randomized clinical trials.

摘要

对于颅外颈动脉狭窄的治疗,颈动脉支架置入术(CAS)已成为一种有用且潜在侵入性较小的替代颈动脉内膜切除术(CEA)的方法。在这方面,有人提出,可能从CAS中获益的特定患者亚组包括那些有严重内科合并症、复发性狭窄、解剖位置难以到达的病变以及颈部情况复杂的患者。然而,本报告的目的也是评估在治疗风险较低的有症状和无症状疾病患者时,CAS是否应该取代CEA。本报告包含了最近发表的随机临床试验的结果。

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