Schlenker B, Gratzke C, Weidlich P, Seitz M, Reich O, Stief C G
Klinik und Poliklinik für Urologie, Klinikum Grosshadern, Ludwig-Maximilians-Universität München.
MMW Fortschr Med. 2007 Aug 16;149(33-34):29-31; quiz 32.
Primary aims of the medical therapy for BPH are improvement of subjective symptoms and quality of life as well as the prevention of long-term complications such as acute urinary retention and renal failure. Secondary goal is inhibition of disease progression. The medical therapy should be tailored to each patient according to the individual complaints and risk of progression. Plant extracts, alpha-blockers and 5-alpha reductase inhibitors represent the most common prescribed substances. Recent data suggest beneficial effects for the use of antimuscarinic agents and phosphodiesterase type 5 inhibitors.
良性前列腺增生症医学治疗的主要目标是改善主观症状和生活质量,以及预防诸如急性尿潴留和肾衰竭等长期并发症。次要目标是抑制疾病进展。医学治疗应根据每位患者的个体主诉和疾病进展风险进行个体化调整。植物提取物、α受体阻滞剂和5α还原酶抑制剂是最常用的处方药。近期数据表明,使用抗毒蕈碱药物和5型磷酸二酯酶抑制剂具有有益效果。