Rosati Maurizio, Vigone Alessandro, Capobianco Francesco, Surico Daniela, Amoruso Elena, Surico Nicola
Department of Obstetrics and Gynecology, San Camillo Hospital, Trento, Italy.
Eur J Obstet Gynecol Reprod Biol. 2008 Jun;138(2):222-5. doi: 10.1016/j.ejogrb.2007.08.013. Epub 2007 Oct 29.
To describe the three-step hysteroscopic endometrial ablation (EA) technique without endometrial preparation, and its long-term outcomes.
Four hundred and thirty-eight premenopausal women with menorrhagia or menometrorrhagia underwent three-step hysteroscopic EA, which consists of rollerball ablation of the fundus and cornual regions, a cutting loop endomyometrial resection of the rest of the cavity, and rollerball redessication of the whole pre-ablated uterine cavity. The main outcome measures were menstrual status, level of satisfaction with the procedure, and the need for repeat ablation or hysterectomy. Questionnaires were completed for 385 women (87.9%) with a mean follow-up of 48.2 months.
One hundred and eighty-four responders (47.8%) reported amenorrhea; 177 (46%) had light to normal flow. One patient (0.3%) underwent repeat ablation and 20 (5.2%) underwent hysterectomy: 15 (3.9%) because of endometrial ablation failure and 5 (1.3%) because of indications unrelated to the ablation (three cases of atypical endometrial hyperplasia and two cases of fibroids). Two hundred and ninety-two patients (75.8%) were very satisfied, and 78 (20.3%) satisfied with the results. No major complications occurred and three women (0.8%) became pregnant during the follow-up period.
EA is safe and effective means of treating of menorrhagia and menometrorrhagia in premenopausal women, and helps avoid hysterectomy in 95% of patients suffering from heavy bleeding, with or without uterine fibroids. Women should be informed that the procedure is not contraceptive and that pregnancy is possible after treatment.
描述无子宫内膜预处理的三步宫腔镜子宫内膜切除术(EA)技术及其长期效果。
438例绝经前月经过多或月经频发的妇女接受了三步宫腔镜EA,该技术包括用滚球电极烧灼宫底和宫角区域、用切割环切除宫腔其余部位的内膜及肌层、用滚球电极再次烧灼整个预先烧灼过的子宫腔。主要观察指标为月经状况、对手术的满意度以及再次切除或子宫切除的必要性。对385例妇女(87.9%)进行了问卷调查,平均随访48.2个月。
184例(47.8%)应答者报告闭经;177例(46%)月经量少至正常。1例患者(0.3%)接受了再次切除,20例(5.2%)接受了子宫切除:15例(3.9%)因子宫内膜切除失败,5例(1.3%)因与切除无关的指征(3例非典型子宫内膜增生和2例肌瘤)。292例患者(75.8%)非常满意,78例(20.3%)对结果满意。未发生重大并发症,3例妇女(共0.8%)在随访期间怀孕。
EA是治疗绝经前妇女月经过多和月经频发的安全有效方法,有助于95%有或无子宫肌瘤的严重出血患者避免子宫切除。应告知妇女该手术不具有避孕作用,术后仍有可能怀孕。