经胸超声心动图测量首次前壁心肌梗死后冠状窦血流量及其与室壁运动评分指数的相关性

Measurement of coronary sinus blood flow after first anterior myocardial infarction with transthoracic echocardiography and its correlation with wall motion scoring index.

作者信息

Toufan Mehrnoush, Samadikhah Jahanbakhsh, Alizadeh-Asl Azin, Azarfarin Rasoul, Hakim Seyed-Hadi, Yaghoubi Alireza, Farzam Saeed

机构信息

Department of Cardiology, Cardiovascular Research Center of Tabriz University of Medical Sciences, Tabriz, Iran.

出版信息

Saudi Med J. 2007 Oct;28(10):1545-9.

PMID:17914518

Abstract

OBJECTIVE

To measure the coronary sinus blood flow (CSBF) and coronary sinus velocity time integral (CSVTI) via transthoracic echocardiography (TTE) in patients with acute myocardial infarction (AMI) in association with the left ventricular ejection fraction (LVEF), and wall motion scoring index (WMSI).

METHODS

In this case-control study, 20 patients with anterior AMI and 20 healthy individuals as the control group, were studied in 6 months period from March to September 2005 in Madani Heart Center, Tabriz, Iran. All patients received the same treatment for AMI (such as fibrinolytic). The CSBF, CSVTI, WMSI, and tissue Doppler imaging (TDI) data were obtained via TTE and compared between the 2 groups.

RESULTS

Baseline variables were similar between the 2 groups (p>0.05). The CSBF in AMI group was 287.8 +/- 128 ml/min and in the control group was 415 +/- 127 ml/min (p=0.001). Also, CSVTI was significantly lower in AMI group than control group (11.16 +/- 2.85 and 17.56 +/- 2.72 mm, p=0.003). There was a significant correlation between CSBF and LVEF (r=0.52, p=0.01), WMSI (r=-0.77, p=0.0001) and CSBF and in-hospital mortality (r=0.58 p=0.03), also between CSVTI and LVEF (r=0.85, p=0.0001), WMSI (r=-0.57, p=0.0009) and in-hospital mortality rate (r=0.69, p=0.02). The CSBF and CSVTI had a good correlation with TDI findings: peak early diastolic velocity in the myocardium and peak systolic velocity in the myocardium).

CONCLUSION

Our study demonstrated a good correlation between measured CSBF and CSVTI by 2D- Doppler TTE and LVEF, WMSI, in-hospital mortality and TDI findings.

摘要

目的

通过经胸超声心动图（TTE）测量急性心肌梗死（AMI）患者的冠状窦血流量（CSBF）和冠状窦速度时间积分（CSVTI），并与左心室射血分数（LVEF）和室壁运动评分指数（WMSI）进行关联分析。

方法

在这项病例对照研究中，选取20例前壁AMI患者和20例健康个体作为对照组，于2005年3月至9月期间在伊朗大不里士的马达尼心脏中心进行为期6个月的研究。所有患者均接受相同的AMI治疗（如溶栓治疗）。通过TTE获取CSBF、CSVTI、WMSI和组织多普勒成像（TDI）数据，并在两组之间进行比较。

结果

两组的基线变量相似（p>0.05）。AMI组的CSBF为287.8±128 ml/min，对照组为415±127 ml/min（p=0.001）。此外，AMI组的CSVTI显著低于对照组（11.16±2.85和17.56±2.72 mm，p=0.003）。CSBF与LVEF（r=0.52，p=0.01）、WMSI（r=-0.77，p=0.0001）以及CSBF与院内死亡率（r=0.58，p=0.03）之间存在显著相关性，CSVTI与LVEF（r=0.85，p=0.0001）、WMSI（r=-0.57，p=0.0009）以及院内死亡率（r=0.69，p=0.02）之间也存在显著相关性。CSBF和CSVTI与TDI结果具有良好的相关性：心肌舒张早期峰值速度和心肌收缩期峰值速度）。