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薄荷醇香烟与非裔美国轻度吸烟者戒烟之间的关系。

Relationship between menthol cigarettes and smoking cessation among African American light smokers.

作者信息

Okuyemi Kolawole S, Faseru Babalola, Sanderson Cox Lisa, Bronars Carrie A, Ahluwalia Jasjit S

机构信息

Program in Health Disparities Research, University of Minnesota Medical School, Minneapolis, MN 55455, USA.

出版信息

Addiction. 2007 Dec;102(12):1979-86. doi: 10.1111/j.1360-0443.2007.02010.x. Epub 2007 Oct 4.

Abstract

AIMS

To determine whether African American light smokers who smoked menthol cigarettes had lower cessation when treated with nicotine replacement therapy and counseling.

DESIGN

Data were derived from a clinical trial that assessed the efficacy of 2 mg nicotine gum (versus placebo) and counseling (motivational interviewing counseling versus Health Education) for smoking cessation among African American light smokers (smoked < or = 10 cigarettes per day).

PARTICIPANTS

The sample consisted of 755 African American light smokers.

MEASUREMENTS

The primary outcome variable was verified 7-day point-prevalence smoking cessation at 26 weeks follow-up. Verification was by salivary cotinine.

FINDINGS

Compared to non-menthol smokers, menthol smokers were younger and less confident to quit smoking (P = 0.023). At 26 weeks post-randomization, 7-day verified abstinence rate was significantly lower for menthol smokers (11.2% versus 18.8% for non-menthol, P = 0.015).

CONCLUSIONS

Among African American light smokers, use of menthol cigarettes is associated with lower smoking cessation rates. Because the majority of African American smokers use menthol cigarettes, a better understanding of the mechanism for this lower quit rate is needed.

摘要

目的

确定使用尼古丁替代疗法和咨询服务时,吸薄荷醇香烟的非裔美国轻度吸烟者戒烟成功率是否较低。

设计

数据来源于一项临床试验,该试验评估了2毫克尼古丁口香糖(与安慰剂相比)以及咨询服务(动机性访谈咨询与健康教育相比)对非裔美国轻度吸烟者(每天吸烟≤10支)戒烟的效果。

参与者

样本包括755名非裔美国轻度吸烟者。

测量方法

主要结局变量是在26周随访时经核实的7天点患病率戒烟情况。通过唾液可替宁进行核实。

研究结果

与非薄荷醇吸烟者相比,薄荷醇吸烟者更年轻,戒烟信心更低(P = 0.023)。随机分组后26周时,薄荷醇吸烟者经核实的7天戒烟率显著较低(分别为11.2%和18.8%,P = 0.015)。

结论

在非裔美国轻度吸烟者中,吸薄荷醇香烟与较低的戒烟率相关。由于大多数非裔美国吸烟者吸薄荷醇香烟,因此需要更好地了解戒烟率较低的机制。

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