Okuyemi Kolawole S, Faseru Babalola, Sanderson Cox Lisa, Bronars Carrie A, Ahluwalia Jasjit S
Program in Health Disparities Research, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
Addiction. 2007 Dec;102(12):1979-86. doi: 10.1111/j.1360-0443.2007.02010.x. Epub 2007 Oct 4.
To determine whether African American light smokers who smoked menthol cigarettes had lower cessation when treated with nicotine replacement therapy and counseling.
Data were derived from a clinical trial that assessed the efficacy of 2 mg nicotine gum (versus placebo) and counseling (motivational interviewing counseling versus Health Education) for smoking cessation among African American light smokers (smoked < or = 10 cigarettes per day).
The sample consisted of 755 African American light smokers.
The primary outcome variable was verified 7-day point-prevalence smoking cessation at 26 weeks follow-up. Verification was by salivary cotinine.
Compared to non-menthol smokers, menthol smokers were younger and less confident to quit smoking (P = 0.023). At 26 weeks post-randomization, 7-day verified abstinence rate was significantly lower for menthol smokers (11.2% versus 18.8% for non-menthol, P = 0.015).
Among African American light smokers, use of menthol cigarettes is associated with lower smoking cessation rates. Because the majority of African American smokers use menthol cigarettes, a better understanding of the mechanism for this lower quit rate is needed.
确定使用尼古丁替代疗法和咨询服务时,吸薄荷醇香烟的非裔美国轻度吸烟者戒烟成功率是否较低。
数据来源于一项临床试验,该试验评估了2毫克尼古丁口香糖(与安慰剂相比)以及咨询服务(动机性访谈咨询与健康教育相比)对非裔美国轻度吸烟者(每天吸烟≤10支)戒烟的效果。
样本包括755名非裔美国轻度吸烟者。
主要结局变量是在26周随访时经核实的7天点患病率戒烟情况。通过唾液可替宁进行核实。
与非薄荷醇吸烟者相比,薄荷醇吸烟者更年轻,戒烟信心更低(P = 0.023)。随机分组后26周时,薄荷醇吸烟者经核实的7天戒烟率显著较低(分别为11.2%和18.8%,P = 0.015)。
在非裔美国轻度吸烟者中,吸薄荷醇香烟与较低的戒烟率相关。由于大多数非裔美国吸烟者吸薄荷醇香烟,因此需要更好地了解戒烟率较低的机制。