一名患有线粒体脂肪酸氧化先天性缺陷的儿童发生嗜水气单胞菌败血症。

Ochrobactrum anthropi bacteremia in a child with inborn error of mitochondrial fatty acid oxidation.

作者信息

Aly Nasser Yehia A, Salmeen Hadeel N, Joshi Rajinder M

机构信息

Department of Tropical Medicine and Hygiene, Faculty of Medicine, University of Alexandria, Alexandria, Egypt.

出版信息

Med Princ Pract. 2007;16(6):463-5. doi: 10.1159/000107753.

DOI:10.1159/000107753

PMID:17917448

Abstract

OBJECTIVE

To report an incident of bacteremia caused by Ochrobactrum anthropi.

CASE PRESENTATION AND INTERVENTION

The case of a female child aged 2 years and 10 months with a known history of long-chain 3-hydroxyacyl-coenzyme A dehydrogenase deficiency who developed O. anthropi bacteremia during hospital stay is presented. Patient's history, clinical findings, laboratory and radiological investigations were thoroughly reviewed. The cultured organism was identified using MicroScan WalkAway 96 SI (Dade Behring) as well as by conventional techniques. Imipenem resistance was confirmed by the conventional Kirby-Bauer disk diffusion technique on Muller-Hinton agar with no zone of inhibition around a 10-mug imipenem disk (Hi Media) using the 0.5 McFarland standard.

CONCLUSION

This report shows O. anthropi as a rare nosocomial pathogen that affected a patient who was immunocompromised. The O. anthropi showed multidrug resistance.

摘要

目的

报告1例嗜水气单胞菌引起的菌血症事件。

病例介绍与干预

介绍了1例2岁10个月女童的病例，该女童有长链3-羟基酰基辅酶A脱氢酶缺乏症病史，住院期间发生嗜水气单胞菌菌血症。对患者的病史、临床症状、实验室及影像学检查进行了全面回顾。使用MicroScan WalkAway 96 SI（达德拜灵公司）以及传统技术对培养出的微生物进行鉴定。采用传统的 Kirby-Bauer 纸片扩散法在穆勒-欣顿琼脂上确认亚胺培南耐药性，使用0.5麦氏标准，在含10μg亚胺培南纸片（Hi Media）周围未出现抑菌圈。