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皮下注射免疫球蛋白:慢性炎症性脱髓鞘性多发性神经病的一种新治疗选择。

Subcutaneous immunoglobulin infusion: a new therapeutic option in chronic inflammatory demyelinating polyneuropathy.

作者信息

Lee De-Hyung, Linker Ralf A, Paulus Walter, Schneider-Gold Christiane, Chan Andrew, Gold Ralf

机构信息

Department of Neurology at St. Josef-Hospital, Ruhr-University Bochum, Gudrunstrasse 56, D-44791 Bochum, Germany.

出版信息

Muscle Nerve. 2008 Mar;37(3):406-9. doi: 10.1002/mus.20909.

Abstract

Intravenous application of immunoglobulins (IVIg) is an effective and usually well tolerated yet costly therapeutic regimen in chronic inflammatory demyelinating polyneuropathy (CIDP). We report two CIDP patients treated with subcutaneous infusion of immunoglobulins (SCIg) after IVIg therapy was shown to be effective. Application of SCIg was well tolerated, easy to manage, and led to stabilization of the disease course. SCIg may represent an effective new therapeutic option in CIDP and is associated with a cost reduction of at least 50% compared to IVIg therapy.

摘要

静脉注射免疫球蛋白(IVIg)在慢性炎性脱髓鞘性多发性神经病(CIDP)的治疗中是一种有效且通常耐受性良好但成本高昂的治疗方案。我们报告了两名CIDP患者,在IVIg治疗显示有效后,接受了皮下注射免疫球蛋白(SCIg)治疗。SCIg的应用耐受性良好,易于管理,并使病程稳定。与IVIg治疗相比,SCIg可能是CIDP一种有效的新治疗选择,且成本降低至少50%。

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