培美曲塞为基础的化疗用于恶性胸膜间皮瘤（MPM）的再治疗：一种二线治疗选择。
Retreatment with pemetrexed-based chemotherapy in malignant pleural mesothelioma (MPM): a second line treatment option.
作者信息
Razak Albiruni Ryan Abdul, Chatten Katy J, Hughes Andrew N
机构信息
Medical Oncology Department, Northern Centre for Cancer Treatment, Newcastle General Hospital, Newcastle upon Tyne NE4 9XF, United Kingdom.
出版信息
Lung Cancer. 2008 May;60(2):294-7. doi: 10.1016/j.lungcan.2007.08.031. Epub 2007 Oct 4.
The role of second line treatment in malignant pleural mesothelioma (MPM) is currently undefined. We present four cases of patients who had durable responses from pemetrexed-based chemotherapy who were retreated with a similar regimen upon progression of their mesothelioma. This case series explores the possible role of retreatment with pemetrexed-based chemotherapy as a second line therapeutic option in MPM.
二线治疗在恶性胸膜间皮瘤（MPM）中的作用目前尚不明确。我们报告了4例患者，他们接受培美曲塞化疗后取得了持久疗效，在间皮瘤进展后再次接受了类似方案的治疗。本病例系列探讨了以培美曲塞为基础的化疗作为MPM二线治疗选择进行再治疗的可能作用。
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