哺乳动物染色单体中端粒环的同位动力学。

Homotopic dynamics of telomeric loops in mammalian chromatids.

作者信息

Jabbour M N, Matioli G T

机构信息

Department of Neurological Surgery, USC Keck School of Medicine, 2025 Zonal Avenue, RMR 424, Los Angeles, CA 90033, USA.

出版信息

J Theor Biol. 2007 Dec 7;249(3):500-2. doi: 10.1016/j.jtbi.2007.08.031. Epub 2007 Sep 7.

DOI:10.1016/j.jtbi.2007.08.031

PMID:17920079

Abstract

Asymmetric transfer of a solitonic kink between telomeric loops shared by template-replica chromatids is conceptualized in terms of homotopic dynamics. Downscaled to B-Z DNA these ideas lead to interesting possibilities regarding duplication and/or selective activation of genes located at or near DNA "hybrid" chiralities.

摘要

模板复制染色单体共享的端粒环之间孤子扭结的不对称转移是根据同伦动力学概念化的。缩小到B-Z DNA，这些想法导致了关于位于DNA“杂交”手性处或附近的基因复制和/或选择性激活的有趣可能性。