Sonnesen Liselotte, Kjaer Inger
Department of Orthodontics, Copenhagen School of Dentistry, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark.
Am J Orthod Dentofacial Orthop. 2007 Oct;132(4):427.e7-12. doi: 10.1016/j.ajodo.2007.01.019.
The cervical column morphology of adults with skeletal Class III malocclusion and mandibular overjet was examined and compared with the cervical column morphology of a control group with neutral occlusion and normal craniofacial morphology.
The mandibular overjet group consisted of 57 patients (32 women, 25 men). The control group consisted of 21 subjects (15 women, 6 men). A visual assessment of the cervical column and measurements of the craniofacial dimensions were performed on a profile radiograph of each subject.
In the mandibular overjet group, 61.4% had cervical column fusion, and 12.3% had posterior arch deficiency. Morphologic cervical column deviations occurred significantly more often in the mandibular overjet group than in the control group (P <.001). The most important craniofacial parameters for fusion of the cervical column were maxillary retrognathism (P <.05) and mandibular overjet (P <.05) (R2 = 0.22). The most important factor for posterior arch deficiency was mandibular inclination (P <.05) (R2 = 0.12).
These results are considered an important first step in phenotypic differentiation of skeletal Class III malocclusions that can be associated with different genotypes. This is important for the diagnosis and the correct treatment of these patients.
对患有骨骼Ⅲ类错颌畸形和下颌前突的成年人的颈椎形态进行了检查，并与具有中性咬合和正常颅面形态的对照组的颈椎形态进行了比较。
下颌前突组由57名患者组成（32名女性，25名男性）。对照组由21名受试者组成（15名女性，6名男性）。对每个受试者的侧位X线片进行颈椎的视觉评估和颅面尺寸测量。
在下颌前突组中，61.4%的患者存在颈椎融合，12.3%的患者存在后弓缺损。下颌前突组形态学颈椎偏差的发生率明显高于对照组（P <.001）。颈椎融合最重要的颅面参数是上颌后缩（P <.05）和下颌前突（P <.05）（R2 = 0.22）。后弓缺损最重要的因素是下颌倾斜度（P <.05）（R2 = 0.12）。
这些结果被认为是骨骼Ⅲ类错颌畸形表型分化的重要第一步，这些错颌畸形可能与不同的基因型相关。这对这些患者的诊断和正确治疗很重要。
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