Sundt Thoralf M
Division of Cardiovascular Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota 55905, USA.
Curr Opin Cardiol. 2007 Nov;22(6):504-9. doi: 10.1097/HCO.0b013e3282f0fd72.
With advances in imaging technology, increased attention has turned to the 'variant forms' of aortic dissection: intramural hematoma and penetrating aortic ulcer. At the same time, the advent of endovascular therapies such as stent-grafting has broadened the base of practitioners capable of intervening in these pathologies from the cardiovascular surgeon to now include vascular surgeons, interventional radiologists, and invasive cardiologists. Accordingly, a reassessment of these conditions is of general interest.
The natural history of both entities is being elucidated with increasing precision as relatively large single-center and multicenter studies are being reported. Recent attention has focused on application of endovascular technologies to penetrating aortic ulcer, while the principal controversy over intramural hematoma concerns its management when the ascending aorta is involved.
Despite continuing controversy over the outcome of penetrating aortic ulcer managed by medical or open surgical means, thoracic endograft technology is being applied to this entity with high procedural success and low perioperative morbidity by experienced teams internationally. The benefit to patients as the use of this technology expands, however, will depend critically upon selection criteria. Evidence in favor of surgical management of type A intramural hematoma continues to mount, although it is also clear that, in specific circumstances, a nonoperative approach may suffice.
随着成像技术的进步,人们越来越关注主动脉夹层的“变异形式”:壁内血肿和穿透性主动脉溃疡。与此同时,诸如支架植入等血管内治疗方法的出现,拓宽了能够干预这些病变的从业者范围,从心血管外科医生扩大到现在的血管外科医生、介入放射科医生和侵入性心脏病专家。因此,对这些病症进行重新评估具有普遍意义。
随着相对大型的单中心和多中心研究报告的出现,这两种病症的自然史正得到越来越精确的阐释。最近的关注焦点在于血管内技术在穿透性主动脉溃疡中的应用,而壁内血肿的主要争议在于当升主动脉受累时的处理方法。
尽管对于采用内科或开放手术方式治疗穿透性主动脉溃疡的疗效仍存在争议,但国际上经验丰富的团队将胸段血管内移植物技术应用于该病症时,手术成功率高且围手术期发病率低。然而,随着这项技术应用范围的扩大,对患者的益处将严重取决于选择标准。支持对A型壁内血肿进行手术治疗的证据不断增加,不过同样明确的是,在特定情况下,非手术方法可能就足够了。