Monneuse O, Gruner L, Barth X, Malick P, Timsit M, Gignoux B, Tissot E
Service d'Urgences Chirurgicales Viscérales, Hôpital Edouard Herriot - Lyon.
J Chir (Paris). 2007 Jul-Aug;144(4):307-12. doi: 10.1016/s0021-7697(07)91959-6.
Gas gangrene of the abdominal wall is a rare clinical occurrence with high rates of morbidity and mortality. The primary source of the infection is often unknown. To analyze the primary underlying intestinal etiologies and diagnostic approaches of gas gangrene of the abdominal wall, and to highlight specific treatment problems, particularly that of constructing a colostomy exteriorized through a massively infected abdominal wall.
Seven cases of abdominal wall gas gangrene due to a gastrointestinal etiology were identified. (Cases arising from proctologic sources or related to recent abdominal surgery were excluded.) During the same period, 39 other patients presenting with abdominal wall gangrene from non-intestinal sources were treated.
The etiologies were: perforated sigmoid diverticulitis (n=2), perforated appendicitis (n=1), acute pancreatitis with associated cecal perforation (n=1), and perforated colorectal cancer (n=3). Four of the seven patients died despite treatment (mortality of 57%).
The clinical presentations of these seven cases demonstrate that a GI source must be suspected whenever a patient presents with abdominal wall gas gangrene, even when there are no specific GI symptoms. Imaging, particularly with CT scan, is essential both to visualize the extent of tissue necrosis and to reveal underlying primary GI pathology. This optimizes the surgical approach both by allowing for complete debridement and drainage of infected tissue, and by focussing the intervention on correction of the underlying primary GI source of infection.
腹壁气性坏疽是一种临床罕见的疾病,发病率和死亡率很高。感染的主要来源往往不明。分析腹壁气性坏疽的主要潜在肠道病因及诊断方法,并强调具体的治疗问题,特别是通过严重感染的腹壁行结肠造口术的问题。
确定7例因胃肠道病因导致的腹壁气性坏疽病例。(排除直肠来源或与近期腹部手术相关的病例。)同期,治疗了39例其他非肠道来源的腹壁坏疽患者。
病因包括:乙状结肠憩室穿孔(2例)、阑尾炎穿孔(1例)、急性胰腺炎伴盲肠穿孔(1例)、结直肠癌穿孔(3例)。7例患者中有4例尽管接受了治疗仍死亡(死亡率为57%)。
这7例病例的临床表现表明,无论患者有无特定的胃肠道症状,只要出现腹壁气性坏疽,就必须怀疑胃肠道来源。影像学检查,尤其是CT扫描,对于观察组织坏死范围和揭示潜在的原发性胃肠道病变至关重要。这既能通过彻底清创和引流感染组织来优化手术方法,又能将干预重点放在纠正潜在的原发性胃肠道感染源上。