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原发性与继发性心力衰竭诊断患者中血管紧张素转换酶抑制剂或血管紧张素受体阻滞剂的依从性

Angiotensin-converting enzyme inhibitor or angiotensin receptor blocker adherence in patients with primary versus secondary diagnosis of heart failure.

作者信息

Brackbill Marcia L, Bashaw-Keaton Rebecca, Sytsma Christine S

机构信息

Bernard J. Dunn School of Pharmacy, Shenandoah University, Winchester, VA 22601, USA.

出版信息

Am J Manag Care. 2007 Oct;13(10):568-70.

Abstract

CONTEXT

It is unknown whether hospitalization for a secondary diagnosis of heart failure (HF) impacts adherence to current HF guidelines. National HF databases that benchmark quality of care currently do not report on adherence based on whether HF is the primary or secondary diagnosis.

OBJECTIVE

To describe angiotensin-converting enzyme inhibitor (ACEI) or angiotensin receptor blocker (ARB) utilization at time of discharge in hospitalized patients with a primary or secondary diagnosis of systolic HF.

STUDY DESIGN

Six-month observational chart review.

METHODS

Patients were included if they were hospitalized with a primary or secondary diagnosis of HF, had an ejection fraction of < or =40%, and were more than 18 years of age. Guideline adherence was defined as appropriate if an ACEI or ARB was prescribed at discharge or if there was a documented contraindication.

RESULTS

Of 204 patients in the study, 170 and 34 patients had a primary or secondary diagnosis of HF, respectively. Eighty-six percent of patients with a primary diagnosis of HF were discharged with an ACEI or ARB, whereas 71% of patients with a secondary diagnosis of HF were discharged with an ACEI or ARB (P = .029).

CONCLUSION

Patients with a primary diagnosis of HF are more likely to be discharged on an ACEI or ARB (if indicated) than those with a secondary diagnosis. Identifying and evaluating the need for an ACEI or ARB in hospitalized patients with a secondary diagnosis of HF offers practitioners an opportunity for improved patient care through better adherence to national guidelines.

摘要

背景

因心力衰竭(HF)二级诊断而住院是否会影响对当前HF指南的遵循情况尚不清楚。目前用于衡量医疗质量的国家HF数据库并未根据HF是主要诊断还是次要诊断来报告遵循情况。

目的

描述原发性或继发性收缩期HF住院患者出院时血管紧张素转换酶抑制剂(ACEI)或血管紧张素受体阻滞剂(ARB)的使用情况。

研究设计

为期6个月的观察性病历回顾。

方法

纳入标准为因原发性或继发性HF住院、射血分数≤40%且年龄超过18岁的患者。如果出院时开具了ACEI或ARB,或者有记录在案的禁忌症,则指南遵循情况被定义为适当。

结果

在该研究的204例患者中,分别有170例和34例患者患有原发性或继发性HF。原发性HF诊断患者中有86%出院时使用了ACEI或ARB,而继发性HF诊断患者中有71%出院时使用了ACEI或ARB(P = 0.029)。

结论

原发性HF诊断患者比继发性诊断患者更有可能在出院时使用ACEI或ARB(如果有指征)。识别和评估继发性HF诊断住院患者对ACEI或ARB的需求,为从业者提供了一个通过更好地遵循国家指南来改善患者护理的机会。

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