Zhang Zhao-Hui, Meng Quan-Fei, Chen Ying-Ming
Department of Radiology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, 510080, PR China.
Ai Zheng. 2007 Sep;26(9):1001-4.
BACKGROUND & OBJECTIVE: Imaging studies on rhabdomyosarcoma in the extremities have seldom been reported. This study was to explore the MRI and CT features of rhabdomyosarcoma in the extremities.
MRI and CT data of 9 patients with rhabdomyosarcoma in the extremities were analyzed.
Among the 8 cases that received MRI examination, as compared with muscle, all tumors showed mixed low and intermediate signal intensity on T1WI, with the later being predominant; all tumors showed intermingling areas of hyper-, iso-, and/or hypo-signal intensity on T2WI; after Gd-DTPA injection, all tumors showed strong and heterogeneous enhancement. Five of them showed ill-defined margin and surrounding edema, the other 3 were well-circumscribed without conspicuous edema. Of the 3 cases that received CT examination, all tumors showed both low and intermediate density as compared with muscle on un-enhanced images, with the later being predominant; none of them showed calcification; 2 of them were ill-defined and the other 1 was well-circumscribed. The case that received contrast-enhanced CT examination showed strong and heterogeneous enhancement. Among all 9 cases, 8 showed necrosis or cystic changes, none showed hemorrhage and invasion of adjacent bone, but 3 showed adjacent blood vessel encasement and 1 showed tumor thrombosis in the adjacent vein.
When MRI or CT reveals a soft tissue mass in the extremity with necrosis and strong and heterogeneous enhancement, especially when hemorrhage, calcification and adjacent bone invasion is not present,rhabdomyosarcoma should be considered.
关于四肢横纹肌肉瘤的影像学研究报道较少。本研究旨在探讨四肢横纹肌肉瘤的MRI和CT特征。
分析9例四肢横纹肌肉瘤患者的MRI和CT资料。
8例行MRI检查的病例中,与肌肉相比,所有肿瘤在T1WI上均表现为低信号与等信号混合,以等信号为主;在T2WI上均表现为高、等、低信号混杂;注射Gd-DTPA后,所有肿瘤均表现为明显不均匀强化。其中5例边界不清,周围有水肿,另外3例边界清晰,无明显水肿。3例行CT检查的病例中,平扫时所有肿瘤与肌肉相比均表现为低密度与等密度混合,以等密度为主;均未见钙化;2例边界不清,1例边界清晰。行增强CT检查的病例表现为明显不均匀强化。9例中,8例有坏死或囊变,均未见出血及邻近骨质侵犯,但3例有邻近血管包绕,1例在邻近静脉内见瘤栓形成。
当MRI或CT显示四肢软组织肿块伴坏死及明显不均匀强化,尤其是无出血、钙化及邻近骨质侵犯时,应考虑横纹肌肉瘤。