印记细胞学提高了计算机断层扫描引导下经皮经胸针吸活检的准确性。
Imprint cytology improves accuracy of computed tomography-guided percutaneous transthoracic needle biopsy.
作者信息
Chang Y-C, Yu C-J, Lee W-J, Kuo S-H, Hsiao C-H, Jan I-S, Hu F-C, Liu H-M, Chan W-K, Yang P-C
机构信息
Dept of Medical Imaging, National Taiwan University Hospital and National Taiwan University College of Medicine, Taipei, Taiwan.
出版信息
Eur Respir J. 2008 Jan;31(1):54-61. doi: 10.1183/09031936.00038907. Epub 2007 Oct 10.
The aim of the present study was to investigate whether imprint cytology can improve the diagnostic accuracy of computed tomography-guided transthoracic core biopsy. Between October 1997 and June 2004, thoracic lesions in 622 patients underwent biopsy using 19-gauge coaxial guiding needles and 20-gauge biopsy needles under computed tomography guidance. Touch imprint cytology and histopathology were performed for all biopsy specimens. Of these lesions, 431 (74.1%) were diagnosed as malignant, 151 (25.9%) as benign and 40 (6%) as nondiagnostic. Imprint cytology plus histology shows an improved diagnostic accuracy of 96.4% compared with that of imprint cytology alone (92.3%) or histopathology alone (93.0%). Procedure-related complications requiring further treatment occurred in eight (1.4%) patients. In conclusion, imprint cytology combined with histopathology can improve the diagnostic accuracy of computed tomography-guided transthoracic needle biopsy.
本研究的目的是探讨印记细胞学是否能提高计算机断层扫描引导下经胸芯针活检的诊断准确性。1997年10月至2004年6月期间，622例患者的胸部病变在计算机断层扫描引导下使用19G同轴引导针和20G活检针进行活检。对所有活检标本进行触摸印记细胞学和组织病理学检查。在这些病变中，431例（74.1%）被诊断为恶性，151例（25.9%）为良性，40例（6%）为无法诊断。与单独使用印记细胞学（92.3%）或单独使用组织病理学（93.0%）相比，印记细胞学加组织学显示诊断准确性提高至96.4%。8例（1.4%）患者发生了需要进一步治疗的与操作相关的并发症。总之，印记细胞学联合组织病理学可提高计算机断层扫描引导下经胸针活检的诊断准确性。
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