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[前列腺癌前哨淋巴结清扫术:现状]

[Sentinel node dissection in prostate cancer: current status].

作者信息

Weckermann D, Holl G, Wagner T, Harzmann R

机构信息

Urologische Klinik, Klinikum Augsburg, Stenglinstr 2, 86156, Augsburg, Germany.

出版信息

Urologe A. 2007 Nov;46(11):1500-7. doi: 10.1007/s00120-007-1564-6.

Abstract

Sentinel lymph node (SLN) dissection is an excellent staging procedure with high sensitivity (>95%) for detecting positive nodes. When the sentinel node is negative, there is high certainty that other lymph nodes are also negative. Limitations of this technique include the use of hormone therapy over several months and a preceding transurethral resection or suprapubic adenomectomy. When sentinel node dissection is performed in patients with intermediate and high-risk prostate cancer, it should be kept in mind that when the SLN is positive, other lymph nodes can be positive, too. The positive non-SLN can be located outside the SLN region. Therefore, both sentinel and extended lymph node dissection should be used in men with a higher risk of lymph node metastases.

摘要

前哨淋巴结(SLN)清扫术是一种出色的分期手术,对检测阳性淋巴结具有高敏感性(>95%)。当前哨淋巴结为阴性时,其他淋巴结也为阴性的确定性很高。该技术的局限性包括数月的激素治疗以及先前的经尿道切除术或耻骨上腺瘤切除术。在中高危前列腺癌患者中进行前哨淋巴结清扫术时,应牢记当前哨淋巴结为阳性时,其他淋巴结也可能为阳性。阳性的非前哨淋巴结可能位于前哨淋巴结区域之外。因此,对于有较高淋巴结转移风险的男性,应同时采用前哨淋巴结清扫术和扩大淋巴结清扫术。

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